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• W2258142491 abstract "This thesis is concerned with the investigation of pulsed electric field (PEF) towards biological cells. Biological cells selected in this study are HeLa (cervical cancer) cells. There are two parts of the study, which was involving modeling methods and experimental setup. Modeling method used involves analytical (MATLAB) and numerical (CST®EMS) methods. Both of these methods are to prove the existence of the effect on transmembrane potential changes when subjected exposed to PEF strength. This result can be seen clearly when both method showed the existence of changes effects on transmembrane potential. Therefore, this study continues by identifying an appropriate experimental setup. Experimental setup involves four important parts, the first part is the source of square wave PEF (ECM®830) that can generate until 3kV field strength. Followed by modified EC magnetic chamber with incubator system that has been used in order to exposed HeLa cells to PEF. At the same time this system is coupled with Nikon inverted microscope (Ti-series) for subsequent visualization techniques, image and video. In the early stage, experimental setup was tested by monitoring the proliferation rate of HeLa cells within 0 to 48 hours. Then HeLa cells were tested to look at the swelling effect via PEF exposure. After that, we continued to identify the optimum PEF parameters for reversible condition on HeLa cell. As a result HeLa cells gives a good response at 2.7kV field strength, 30μs pulse length with single pulse. Further study showed that two or more adjacent HeLa cells merge together due to increased cell membrane permeability (electrofusion). This discovery triggered an idea to look at the PEF effect on wound healing process. An artificial wound site were investigated with and without PEF exposure. The finding shows PEF exposed wound area took 3 hours to completely heal while the untreated area took 10 hours. This prove a novel technique (electrical based novel treatment) which could be an alternative to drug usage for wound healing process. Overall, the findings achieved in this study could lead us onto a drug free wound healing method." @default.
• W2258142491 created "2016-06-24" @default.
• W2258142491 creator A5006546865 @default.
• W2258142491 date "2015-04-01" @default.
• W2258142491 modified "2023-09-27" @default.
• W2258142491 title "Pulse electric field exposure effect on morphological properties of HeLa cells" @default.
• W2258142491 cites W102977685 @default.
• W2258142491 cites W117036309 @default.
• W2258142491 cites W1490324405 @default.
• W2258142491 cites W1495278797 @default.
• W2258142491 cites W1524573041 @default.
• W2258142491 cites W1531604089 @default.
• W2258142491 cites W1554324421 @default.
• W2258142491 cites W1599588446 @default.
• W2258142491 cites W1608566434 @default.
• W2258142491 cites W1717716822 @default.
• W2258142491 cites W1849302557 @default.
• W2258142491 cites W185927998 @default.
• W2258142491 cites W1870060710 @default.
• W2258142491 cites W1904722209 @default.
• W2258142491 cites W1964982943 @default.
• W2258142491 cites W1966082088 @default.
• W2258142491 cites W1966300087 @default.
• W2258142491 cites W1966695838 @default.
• W2258142491 cites W1969491501 @default.
• W2258142491 cites W1970967928 @default.
• W2258142491 cites W1971244095 @default.
• W2258142491 cites W1971770277 @default.
• W2258142491 cites W1973142530 @default.
• W2258142491 cites W1974782694 @default.
• W2258142491 cites W1977301908 @default.
• W2258142491 cites W1978148977 @default.
• W2258142491 cites W1978829154 @default.
• W2258142491 cites W1979444189 @default.
• W2258142491 cites W1979953538 @default.
• W2258142491 cites W1980934208 @default.
• W2258142491 cites W1981454713 @default.
• W2258142491 cites W1981471855 @default.
• W2258142491 cites W1984242118 @default.
• W2258142491 cites W1987331471 @default.
• W2258142491 cites W1991289286 @default.
• W2258142491 cites W1991327258 @default.
• W2258142491 cites W1992408109 @default.
• W2258142491 cites W1995106222 @default.
• W2258142491 cites W1997736791 @default.
• W2258142491 cites W1998958973 @default.
• W2258142491 cites W2002622786 @default.
• W2258142491 cites W2004754106 @default.
• W2258142491 cites W2005817273 @default.
• W2258142491 cites W2005839003 @default.
• W2258142491 cites W2007540017 @default.
• W2258142491 cites W2008518368 @default.
• W2258142491 cites W2008800998 @default.
• W2258142491 cites W2008850075 @default.
• W2258142491 cites W2010129818 @default.
• W2258142491 cites W2012140361 @default.
• W2258142491 cites W2012939150 @default.
• W2258142491 cites W2015392719 @default.
• W2258142491 cites W2018983969 @default.
• W2258142491 cites W2022803930 @default.
• W2258142491 cites W2023328439 @default.
• W2258142491 cites W2023585384 @default.
• W2258142491 cites W2023839087 @default.
• W2258142491 cites W2024343837 @default.
• W2258142491 cites W2024657253 @default.
• W2258142491 cites W2026143998 @default.
• W2258142491 cites W2029036292 @default.
• W2258142491 cites W2029812891 @default.
• W2258142491 cites W2032086738 @default.
• W2258142491 cites W2032678451 @default.
• W2258142491 cites W2032782065 @default.
• W2258142491 cites W2032783816 @default.
• W2258142491 cites W2033740339 @default.
• W2258142491 cites W2034684832 @default.
• W2258142491 cites W2035135142 @default.
• W2258142491 cites W2037085464 @default.
• W2258142491 cites W2038696432 @default.
• W2258142491 cites W2039942347 @default.
• W2258142491 cites W2040244293 @default.
• W2258142491 cites W2041405867 @default.
• W2258142491 cites W2042331734 @default.
• W2258142491 cites W2043145714 @default.
• W2258142491 cites W2046445187 @default.
• W2258142491 cites W2046993631 @default.
• W2258142491 cites W2047209444 @default.
• W2258142491 cites W2047256102 @default.
• W2258142491 cites W2049262657 @default.
• W2258142491 cites W2051345355 @default.
• W2258142491 cites W2051839442 @default.
• W2258142491 cites W2054337002 @default.
• W2258142491 cites W2055172359 @default.
• W2258142491 cites W2056104198 @default.
• W2258142491 cites W2057777676 @default.
• W2258142491 cites W2061390043 @default.
• W2258142491 cites W2061415244 @default.
• W2258142491 cites W2063131972 @default.
• W2258142491 cites W2064743024 @default.
• W2258142491 cites W2066418118 @default.
• W2258142491 cites W2069041223 @default.
• W2258142491 cites W2069546260 @default.

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