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- W2258284044 abstract "Morphological changes in the optic nerve were traced in experiments on 20 rabbits subjected to gamma irradiation with Co/sup 60/ in doses of 1000 and 1500 r. Starting at 48 minutes after irradiation, the animals died or were killed over a 15-month period. The eye was fixed in 20% neutral formalin. The frozen sections were impregnated with silver nitrate by the gold-deposition method and the nuclei stained with hematoxylin. Histological changes developed in the optic nerve within 48 minutes after irradiation, taking the form of tissue edema and irritation of the larger fibers. The irritation increased on the 4th day and the fibers exhibited thickening and slight intumescences. Vacuolar dystrophy and disintegration to large fragments were noted on the 6th-12th day. Hyperargentophilia, irregularity of shape, and terminal excrescences of neuroplasm were observed on the 15th-31th day. Irritation and degeneration of small nerve fibers increased. After 15 months the optic nerve still had a normal structure but small fibers predominated in its tracts. (Referativnyy Zhurnal, Biologiya, No. 16, Aug. 1963)" @default.
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- W2258284044 date "1962-01-01" @default.
- W2258284044 modified "2023-09-27" @default.
- W2258284044 title "MORPHOLOGICAL CHANGES IN TEH OPTIC NERVE UNDER THE ACTION OF IONIZING RADIATION" @default.
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