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- W2258366152 abstract "Aims: Homeopathic complex TepeexA‚® is a compound of Actaea racemosa 4cH, Natrum muriaticum 2cH, Pulsatilla nigricans 3cH, Chamomilla 3cH and Sepia succus5cH. This study evaluated the effect of TepeexA‚® in pre-clinical models of depression and anxiety. Methods: the following tests were performed: elevated plus maze test (EPM); forced swimming test (FST); open field test (OFT) and Rotarod test (RRT). Results: In EPM, animals treated with TepeexA‚® on days 20 and 30 stayed longer in the open arms of the maze than the control group (p < 0.05, Dunnett test). In FST, treatment with TepeexA‚® did not increase swimming time compared to the control group in any phase of treatment. In OFT, crossing increased significantly with treatment with amfepramone, and also with 30-day treatment with TepeexA‚® (p < 0.05, Dunnette test). In RRT, treatment with amfepramone significantly reduced latency time. 30-day treatment with TepeexA‚® did not affect motor coordination when compared to the control group. Conclusion: results suggest that homeopathic complex TepeexA‚® has anxiolytic properties without affecting motor coordination." @default.
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- W2258366152 date "2009-09-15" @default.
- W2258366152 modified "2023-09-27" @default.
- W2258366152 title "Anxiolytic effect of the homeopathic complex Tepeex®" @default.
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