FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2258555720> ?p ?o ?g. }

• W2258555720 endingPage "288" @default.
• W2258555720 startingPage "283" @default.
• W2258555720 abstract "Received: Revised: Accepted: August 30, 2014 November 20, 2014 February 07, 2015 Serious lipid mobilization in adipose tissue of dairy cow is the pathological basis of ketosis and fatty liver. Many Studies demonstrated that pre-adipocytes are unstable and can differentiate into multiple cells in vitro. The aim of this study was to investigate the differentiation process of dairy cow pre-adipocytes and to establish a stable pre-adipocyte induction method. Pre-adipocytes were isolated from dairy cow adipose tissue and were cultured for 15 days. The originally rounded cells converted to a spindle fibroblast-like morphology and accumulated lipids during culturing. The lipid droplets and TG content in the adipocytes gradually increased from 4 to 15 days in culture. The adipocytes reached maximal proliferation after 11 days in culture. Additionally, the expression of peroxisome proliferator-activated receptor γ2 (PPARγ2) and sterol regulatory element binding protein 1c (SREBP-1c) increased during the initial 4 days of differentiation and decreased thereafter. However, the level of SREBP-1c increased after 10 days of differentiation. The PPARγ2 and SREBP-1c proteins levels were significantly higher on day 13 than on day 0. PPARγ2 and SREBP-1c were primarily localized to the cytoplasm on day 0 and to the cytoplasm and nucleus on day 13. In conclusion, a stable dairy cow preadipocyte culture was established, and SREBP-1c and PPARγ2 were increased during (demonstrated to be involved in) pre-adipocyte differentiation. Isolated adipocytes can be used as a cellular model to elucidate the process of lipogenesis in dairy cows and to further investigate metabolic diseases. ©2015 PVJ. All rights reserved" @default.
• W2258555720 created "2016-06-24" @default.
• W2258555720 creator A5001713513 @default.
• W2258555720 creator A5030439932 @default.
• W2258555720 creator A5032307162 @default.
• W2258555720 creator A5035423690 @default.
• W2258555720 creator A5050711402 @default.
• W2258555720 creator A5053214705 @default.
• W2258555720 creator A5064840674 @default.
• W2258555720 creator A5076739463 @default.
• W2258555720 creator A5081892881 @default.
• W2258555720 creator A5090731919 @default.
• W2258555720 date "2015-01-01" @default.
• W2258555720 modified "2023-09-27" @default.
• W2258555720 title "The isolation of pre-adipocytes from dairy cow adipose tissue and the development of pre- adipocytes into mature adipocytes." @default.
• W2258555720 cites W1974156337 @default.
• W2258555720 cites W1974867893 @default.
• W2258555720 cites W1990614859 @default.
• W2258555720 cites W1991755362 @default.
• W2258555720 cites W2010894032 @default.
• W2258555720 cites W2019011732 @default.
• W2258555720 cites W2028919685 @default.
• W2258555720 cites W2033204507 @default.
• W2258555720 cites W2045938248 @default.
• W2258555720 cites W2051051060 @default.
• W2258555720 cites W2052142442 @default.
• W2258555720 cites W2056247578 @default.
• W2258555720 cites W2056538040 @default.
• W2258555720 cites W2059992589 @default.
• W2258555720 cites W2071095866 @default.
• W2258555720 cites W2073432398 @default.
• W2258555720 cites W2074404034 @default.
• W2258555720 cites W2074611211 @default.
• W2258555720 cites W2085828619 @default.
• W2258555720 cites W2090526989 @default.
• W2258555720 cites W2123652234 @default.
• W2258555720 cites W2125450965 @default.
• W2258555720 cites W2135133255 @default.
• W2258555720 cites W2146259114 @default.
• W2258555720 cites W2146696861 @default.
• W2258555720 cites W2154399948 @default.
• W2258555720 cites W2154574091 @default.
• W2258555720 cites W2159230151 @default.
• W2258555720 cites W2160106482 @default.
• W2258555720 cites W2162309112 @default.
• W2258555720 hasPublicationYear "2015" @default.
• W2258555720 type Work @default.
• W2258555720 sameAs 2258555720 @default.
• W2258555720 citedByCount "0" @default.
• W2258555720 crossrefType "journal-article" @default.
• W2258555720 hasAuthorship W2258555720A5001713513 @default.
• W2258555720 hasAuthorship W2258555720A5030439932 @default.
• W2258555720 hasAuthorship W2258555720A5032307162 @default.
• W2258555720 hasAuthorship W2258555720A5035423690 @default.
• W2258555720 hasAuthorship W2258555720A5050711402 @default.
• W2258555720 hasAuthorship W2258555720A5053214705 @default.
• W2258555720 hasAuthorship W2258555720A5064840674 @default.
• W2258555720 hasAuthorship W2258555720A5076739463 @default.
• W2258555720 hasAuthorship W2258555720A5081892881 @default.
• W2258555720 hasAuthorship W2258555720A5090731919 @default.
• W2258555720 hasConcept C122927707 @default.
• W2258555720 hasConcept C126322002 @default.
• W2258555720 hasConcept C127078168 @default.
• W2258555720 hasConcept C134018914 @default.
• W2258555720 hasConcept C141359234 @default.
• W2258555720 hasConcept C170493617 @default.
• W2258555720 hasConcept C171089720 @default.
• W2258555720 hasConcept C185592680 @default.
• W2258555720 hasConcept C25095133 @default.
• W2258555720 hasConcept C2776175234 @default.
• W2258555720 hasConcept C71924100 @default.
• W2258555720 hasConcept C86803240 @default.
• W2258555720 hasConcept C95444343 @default.
• W2258555720 hasConceptScore W2258555720C122927707 @default.
• W2258555720 hasConceptScore W2258555720C126322002 @default.
• W2258555720 hasConceptScore W2258555720C127078168 @default.
• W2258555720 hasConceptScore W2258555720C134018914 @default.
• W2258555720 hasConceptScore W2258555720C141359234 @default.
• W2258555720 hasConceptScore W2258555720C170493617 @default.
• W2258555720 hasConceptScore W2258555720C171089720 @default.
• W2258555720 hasConceptScore W2258555720C185592680 @default.
• W2258555720 hasConceptScore W2258555720C25095133 @default.
• W2258555720 hasConceptScore W2258555720C2776175234 @default.
• W2258555720 hasConceptScore W2258555720C71924100 @default.
• W2258555720 hasConceptScore W2258555720C86803240 @default.
• W2258555720 hasConceptScore W2258555720C95444343 @default.
• W2258555720 hasIssue "3" @default.
• W2258555720 hasLocation W22585557201 @default.
• W2258555720 hasOpenAccess W2258555720 @default.
• W2258555720 hasPrimaryLocation W22585557201 @default.
• W2258555720 hasRelatedWork W1882625237 @default.
• W2258555720 hasRelatedWork W1976855578 @default.
• W2258555720 hasRelatedWork W1985405594 @default.
• W2258555720 hasRelatedWork W2007026899 @default.
• W2258555720 hasRelatedWork W2045570112 @default.
• W2258555720 hasRelatedWork W2165871523 @default.
• W2258555720 hasRelatedWork W2325611995 @default.
• W2258555720 hasRelatedWork W2342429512 @default.

• next