Matches in SemOpenAlex for { <https://semopenalex.org/work/W2258835401> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2258835401 endingPage "2913" @default.
- W2258835401 startingPage "2892" @default.
- W2258835401 abstract "The prevalence of fungal infections of skin has increased rapidly, affecting approximately 40 million people across the globe. A wide variety of antifungal drugs has been utilized in the effective management of numerous dermatological infections. Topical treatment of fungal infections has proved to be quite advantageous due to various factors like targeting the site of infection, minimizing systemic side effects, enhanced efficacy of treatment, and improved patient compliance. In spite the fact that these agents are therapeutically active on topical application, these have restricted drug delivery across the skin resulting in insufficient therapeutic index and may exert local as well as systemic side effects. The accomplishment of topical drug delivery needs to pacify two anomalous aspects, first the barrier nature of stratum corneum, and second, deposition of drug within the skin should be ideally achieved with limited percutaneous absorption. Thus, to facilitate the delivery of antifungal drugs and improve the treatment aspects, various novel delivery carriers have been developed. This article attempts to provide an in-depth knowledge of nanoparticulate and vesicular carriers. This article focuses on the different aspects of fungal infections and their effective treatment with antifungal drugs. Efficacy of various carrier systems (nanoparticulate and vesicular carriers) in delivering antifungal drugs topically has also been discussed. Besides, compiling various research reports, this article also includes formulation considerations inclusive of regulatory aspects of excipients used, the mechanisms of penetration, and patents reported. Keywords: Antifungals, delivery systems, fungal diseases, penetration, therapeutics." @default.
- W2258835401 created "2016-06-24" @default.
- W2258835401 creator A5026675928 @default.
- W2258835401 creator A5065732788 @default.
- W2258835401 creator A5079610738 @default.
- W2258835401 date "2015-05-27" @default.
- W2258835401 modified "2023-10-18" @default.
- W2258835401 title "Topical Delivery of Drugs for the Effective Treatment of Fungal Infections of Skin" @default.
- W2258835401 doi "https://doi.org/10.2174/1381612821666150428150456" @default.
- W2258835401 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25925110" @default.
- W2258835401 hasPublicationYear "2015" @default.
- W2258835401 type Work @default.
- W2258835401 sameAs 2258835401 @default.
- W2258835401 citedByCount "34" @default.
- W2258835401 countsByYear W22588354012016 @default.
- W2258835401 countsByYear W22588354012017 @default.
- W2258835401 countsByYear W22588354012018 @default.
- W2258835401 countsByYear W22588354012019 @default.
- W2258835401 countsByYear W22588354012020 @default.
- W2258835401 countsByYear W22588354012021 @default.
- W2258835401 countsByYear W22588354012022 @default.
- W2258835401 countsByYear W22588354012023 @default.
- W2258835401 crossrefType "journal-article" @default.
- W2258835401 hasAuthorship W2258835401A5026675928 @default.
- W2258835401 hasAuthorship W2258835401A5065732788 @default.
- W2258835401 hasAuthorship W2258835401A5079610738 @default.
- W2258835401 hasConcept C142724271 @default.
- W2258835401 hasConcept C16005928 @default.
- W2258835401 hasConcept C171250308 @default.
- W2258835401 hasConcept C177713679 @default.
- W2258835401 hasConcept C192562407 @default.
- W2258835401 hasConcept C2778370115 @default.
- W2258835401 hasConcept C2779548794 @default.
- W2258835401 hasConcept C2779820397 @default.
- W2258835401 hasConcept C2780035454 @default.
- W2258835401 hasConcept C2909719004 @default.
- W2258835401 hasConcept C2909919671 @default.
- W2258835401 hasConcept C71924100 @default.
- W2258835401 hasConcept C98274493 @default.
- W2258835401 hasConceptScore W2258835401C142724271 @default.
- W2258835401 hasConceptScore W2258835401C16005928 @default.
- W2258835401 hasConceptScore W2258835401C171250308 @default.
- W2258835401 hasConceptScore W2258835401C177713679 @default.
- W2258835401 hasConceptScore W2258835401C192562407 @default.
- W2258835401 hasConceptScore W2258835401C2778370115 @default.
- W2258835401 hasConceptScore W2258835401C2779548794 @default.
- W2258835401 hasConceptScore W2258835401C2779820397 @default.
- W2258835401 hasConceptScore W2258835401C2780035454 @default.
- W2258835401 hasConceptScore W2258835401C2909719004 @default.
- W2258835401 hasConceptScore W2258835401C2909919671 @default.
- W2258835401 hasConceptScore W2258835401C71924100 @default.
- W2258835401 hasConceptScore W2258835401C98274493 @default.
- W2258835401 hasIssue "20" @default.
- W2258835401 hasLocation W22588354011 @default.
- W2258835401 hasLocation W22588354012 @default.
- W2258835401 hasOpenAccess W2258835401 @default.
- W2258835401 hasPrimaryLocation W22588354011 @default.
- W2258835401 hasRelatedWork W2000339087 @default.
- W2258835401 hasRelatedWork W2036245773 @default.
- W2258835401 hasRelatedWork W2069898171 @default.
- W2258835401 hasRelatedWork W2413078799 @default.
- W2258835401 hasRelatedWork W2440282503 @default.
- W2258835401 hasRelatedWork W2467687738 @default.
- W2258835401 hasRelatedWork W2899509607 @default.
- W2258835401 hasRelatedWork W4213224952 @default.
- W2258835401 hasRelatedWork W4281562866 @default.
- W2258835401 hasRelatedWork W884630152 @default.
- W2258835401 hasVolume "21" @default.
- W2258835401 isParatext "false" @default.
- W2258835401 isRetracted "false" @default.
- W2258835401 magId "2258835401" @default.
- W2258835401 workType "article" @default.