FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2258902018> ?p ?o ?g. }

• W2258902018 endingPage "64" @default.
• W2258902018 startingPage "55" @default.
• W2258902018 abstract "The hybrid recombinant human interferon (IFN) rIFN-αA/D was radioiodinated. Specific binding of [125I]rIFN-αA/D was observed with both human and murine cell lines. The binding of [125I]rIFN-αA/D to human Daudi cells had similar characteristics to the previously described binding of [125I]rIFN-αA or -α2. The following lines of evidence demonstrated that [125I]rIFN-αA/D bound with high affinity to the same receptor on murine cells as murine IFN-α and -β: (i) the binding of [125I]rIFN-αA/D to murine LBRM cells was inhibited to a similar extent by natural murine IFN-α, natural murine IFN-β, and rIFN-A/D; (ii) the Kd (~2 χ 10−10M) obtained from both competition experiments and saturation binding experiments with [125I]rIFN-αA/D was comparable to the previously reported Kd for the binding of natural murine IFN-α and -β to other murine cell lines; (iii) the size of the cross-linked [125I]rIFN-αA/D receptor complex formed on murine LBRM cells was similar to the previously reported cross-linked complex formed after binding radioiodinated natural murine IFN-β to other murine cell lines. Due to the current lack of readily available recombinant murine IFN-α or -β for radiolabeling and the previously demonstrated biological activity of rIFN-αA/D on murine cells, [125I]rIFN-αA/D should prove to be a useful reagent for further studies of murine IFN receptors." @default.
• W2258902018 created "2016-06-24" @default.
• W2258902018 creator A5021374249 @default.
• W2258902018 creator A5034803944 @default.
• W2258902018 creator A5038948232 @default.
• W2258902018 creator A5040770925 @default.
• W2258902018 creator A5073001403 @default.
• W2258902018 creator A5082076726 @default.
• W2258902018 date "1990-02-01" @default.
• W2258902018 modified "2023-09-25" @default.
• W2258902018 title "Characterization of the Binding of Radioiodinated Hybrid Recombinant IFN-αA/D to Murine and Human Lymphoid Cell Lines" @default.
• W2258902018 cites W1482624499 @default.
• W2258902018 cites W1498949169 @default.
• W2258902018 cites W1499539788 @default.
• W2258902018 cites W1542531015 @default.
• W2258902018 cites W1547436573 @default.
• W2258902018 cites W1556531780 @default.
• W2258902018 cites W1591612106 @default.
• W2258902018 cites W1599468737 @default.
• W2258902018 cites W1604936133 @default.
• W2258902018 cites W1912769169 @default.
• W2258902018 cites W1992781848 @default.
• W2258902018 cites W1997868973 @default.
• W2258902018 cites W1999259276 @default.
• W2258902018 cites W2008057228 @default.
• W2258902018 cites W2013266934 @default.
• W2258902018 cites W2016779172 @default.
• W2258902018 cites W2034425299 @default.
• W2258902018 cites W2037112265 @default.
• W2258902018 cites W2044339218 @default.
• W2258902018 cites W2051556481 @default.
• W2258902018 cites W2064905947 @default.
• W2258902018 cites W2080207655 @default.
• W2258902018 cites W2083934011 @default.
• W2258902018 cites W2105692968 @default.
• W2258902018 cites W2129306453 @default.
• W2258902018 cites W2147818004 @default.
• W2258902018 cites W2167887143 @default.
• W2258902018 cites W2177943720 @default.
• W2258902018 cites W2312446893 @default.
• W2258902018 cites W2313740168 @default.
• W2258902018 cites W2436131331 @default.
• W2258902018 doi "https://doi.org/10.1089/jir.1990.10.55" @default.
• W2258902018 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2139461" @default.
• W2258902018 hasPublicationYear "1990" @default.
• W2258902018 type Work @default.
• W2258902018 sameAs 2258902018 @default.
• W2258902018 citedByCount "3" @default.
• W2258902018 crossrefType "journal-article" @default.
• W2258902018 hasAuthorship W2258902018A5021374249 @default.
• W2258902018 hasAuthorship W2258902018A5034803944 @default.
• W2258902018 hasAuthorship W2258902018A5038948232 @default.
• W2258902018 hasAuthorship W2258902018A5040770925 @default.
• W2258902018 hasAuthorship W2258902018A5073001403 @default.
• W2258902018 hasAuthorship W2258902018A5082076726 @default.
• W2258902018 hasConcept C104317684 @default.
• W2258902018 hasConcept C107824862 @default.
• W2258902018 hasConcept C153911025 @default.
• W2258902018 hasConcept C170493617 @default.
• W2258902018 hasConcept C203014093 @default.
• W2258902018 hasConcept C2778690821 @default.
• W2258902018 hasConcept C2780841837 @default.
• W2258902018 hasConcept C40767141 @default.
• W2258902018 hasConcept C54355233 @default.
• W2258902018 hasConcept C55493867 @default.
• W2258902018 hasConcept C81885089 @default.
• W2258902018 hasConcept C86803240 @default.
• W2258902018 hasConceptScore W2258902018C104317684 @default.
• W2258902018 hasConceptScore W2258902018C107824862 @default.
• W2258902018 hasConceptScore W2258902018C153911025 @default.
• W2258902018 hasConceptScore W2258902018C170493617 @default.
• W2258902018 hasConceptScore W2258902018C203014093 @default.
• W2258902018 hasConceptScore W2258902018C2778690821 @default.
• W2258902018 hasConceptScore W2258902018C2780841837 @default.
• W2258902018 hasConceptScore W2258902018C40767141 @default.
• W2258902018 hasConceptScore W2258902018C54355233 @default.
• W2258902018 hasConceptScore W2258902018C55493867 @default.
• W2258902018 hasConceptScore W2258902018C81885089 @default.
• W2258902018 hasConceptScore W2258902018C86803240 @default.
• W2258902018 hasIssue "1" @default.
• W2258902018 hasLocation W22589020181 @default.
• W2258902018 hasLocation W22589020182 @default.
• W2258902018 hasOpenAccess W2258902018 @default.
• W2258902018 hasPrimaryLocation W22589020181 @default.
• W2258902018 hasRelatedWork W1496743899 @default.
• W2258902018 hasRelatedWork W1619770054 @default.
• W2258902018 hasRelatedWork W1976290442 @default.
• W2258902018 hasRelatedWork W2093292249 @default.
• W2258902018 hasRelatedWork W2356177663 @default.
• W2258902018 hasRelatedWork W2368295268 @default.
• W2258902018 hasRelatedWork W2414070492 @default.
• W2258902018 hasRelatedWork W2417380264 @default.
• W2258902018 hasRelatedWork W2989026115 @default.
• W2258902018 hasRelatedWork W3026200651 @default.
• W2258902018 hasVolume "10" @default.
• W2258902018 isParatext "false" @default.
• W2258902018 isRetracted "false" @default.
• W2258902018 magId "2258902018" @default.

• next