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- W2259065747 abstract "The spliceosome is a large ribonucleoprotein complex composed of five small nuclear RNAs and over fifty proteins and is responsible for the removal of introns from pre-messenger RNA. Spliceosomal introns are prevalent among crown eukaryotes, whereas none has been found in those lineages thought to diverge earliest on the eukaryotic tree. However, the number of protein-coding genes sequenced from early-diverging eukaryotes is relatively low, creating a very small sample size. Since searching for introns directly in these organisms would be a nearly impossible task, I instead searched for evidence of spliceosomal components whose presence would be necessary for intron removal. The presence and conservation of such components could indicate that they are part of functional spliceosomes mediating the removal of spliceosomal introns." @default.
- W2259065747 created "2016-06-24" @default.
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- W2259065747 date "1999-01-01" @default.
- W2259065747 modified "2023-09-27" @default.
- W2259065747 title "Studies on the evolution of the spliceosome and origin of the microsporidia." @default.
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