FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2259086253> ?p ?o ?g. }

• W2259086253 abstract "The 2.9kb Sac I fragment (EJ2.9), which lacks the previously reported promoter/enhancers of the activated human c-H-ras-1, was used to study the interaction with the tumor virus promoter/enhancers or with the activated c-myc. When EJ2.9 constructs linked to the viral promoter/enhancers or to a viral enhancer even in the antisense orientation was transfected to the mouse cells, 16-39% of the foci induced with those linked in the sense orientation were formed. Further, the transforming activity decreased dramatically when the deletion was introduced from the upstream Sac I site to the 61 bases (-61) upstream of translational initiation codon, but the deletions to -144 did not significantly change the activity. Cotransfections with the activated c-myc were found also to enhance the transforming activity of EJ2.9 constructs either with or without the LTR linked in the antisense orientation. The transfected ras and myc were expressed as 1.2 and 2.5kb mRNAs, respectively, in each transformant. The in vitro mutagenesis suggested that the c-myc protein was involved in the enhancement. These results raise the possibility that the viral enhancers activate a cryptic promoter (s) within the region between -1 and -144 of p21 initiation codon by interacting with the region between -61 and -144 and that the c-myc protein also activates the same or different cryptic promoter(s) within the intron 0 or noncoding region of exon I, thus leading to the enhancement of the EJ2.9 transforming activity." @default.
• W2259086253 created "2016-06-24" @default.
• W2259086253 creator A5089062848 @default.
• W2259086253 date "1990-01-01" @default.
• W2259086253 modified "2023-09-23" @default.
• W2259086253 title "Enhancement of Cellular Transforming Activities of Truncated EJ c-H-ras-1 with Viral Enhancers or with c-myc." @default.
• W2259086253 cites W1043265801 @default.
• W2259086253 cites W1409780570 @default.
• W2259086253 cites W1499029650 @default.
• W2259086253 cites W1648218735 @default.
• W2259086253 cites W1738758476 @default.
• W2259086253 cites W1805591761 @default.
• W2259086253 cites W1893545268 @default.
• W2259086253 cites W1954929088 @default.
• W2259086253 cites W1987600685 @default.
• W2259086253 cites W1989009382 @default.
• W2259086253 cites W1996729627 @default.
• W2259086253 cites W1997940906 @default.
• W2259086253 cites W2001923549 @default.
• W2259086253 cites W2004771750 @default.
• W2259086253 cites W2011836510 @default.
• W2259086253 cites W2013973825 @default.
• W2259086253 cites W2016167564 @default.
• W2259086253 cites W2016505381 @default.
• W2259086253 cites W2025674096 @default.
• W2259086253 cites W2028519621 @default.
• W2259086253 cites W2032354502 @default.
• W2259086253 cites W2034647136 @default.
• W2259086253 cites W2035208645 @default.
• W2259086253 cites W2040714157 @default.
• W2259086253 cites W2041779329 @default.
• W2259086253 cites W2054567381 @default.
• W2259086253 cites W2054876743 @default.
• W2259086253 cites W2061429557 @default.
• W2259086253 cites W2065744098 @default.
• W2259086253 cites W2066569231 @default.
• W2259086253 cites W2072791895 @default.
• W2259086253 cites W2082383547 @default.
• W2259086253 cites W2090968423 @default.
• W2259086253 cites W2106495814 @default.
• W2259086253 cites W2107366537 @default.
• W2259086253 cites W2118929543 @default.
• W2259086253 cites W2133508418 @default.
• W2259086253 cites W2138270253 @default.
• W2259086253 cites W2159594827 @default.
• W2259086253 cites W2160550943 @default.
• W2259086253 cites W2165305811 @default.
• W2259086253 cites W2165781463 @default.
• W2259086253 cites W2169413646 @default.
• W2259086253 cites W2222548685 @default.
• W2259086253 cites W2460318688 @default.
• W2259086253 doi "https://doi.org/10.5357/koubyou.57.562" @default.
• W2259086253 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2081937" @default.
• W2259086253 hasPublicationYear "1990" @default.
• W2259086253 type Work @default.
• W2259086253 sameAs 2259086253 @default.
• W2259086253 citedByCount "0" @default.
• W2259086253 crossrefType "journal-article" @default.
• W2259086253 hasAuthorship W2259086253A5089062848 @default.
• W2259086253 hasBestOaLocation W22590862531 @default.
• W2259086253 hasConcept C101762097 @default.
• W2259086253 hasConcept C104317684 @default.
• W2259086253 hasConcept C105580179 @default.
• W2259086253 hasConcept C111936080 @default.
• W2259086253 hasConcept C138885662 @default.
• W2259086253 hasConcept C143141573 @default.
• W2259086253 hasConcept C147789679 @default.
• W2259086253 hasConcept C150194340 @default.
• W2259086253 hasConcept C153911025 @default.
• W2259086253 hasConcept C176990463 @default.
• W2259086253 hasConcept C179926584 @default.
• W2259086253 hasConcept C185592680 @default.
• W2259086253 hasConcept C41895202 @default.
• W2259086253 hasConcept C54009773 @default.
• W2259086253 hasConcept C54355233 @default.
• W2259086253 hasConcept C86339819 @default.
• W2259086253 hasConcept C86803240 @default.
• W2259086253 hasConcept C94671646 @default.
• W2259086253 hasConceptScore W2259086253C101762097 @default.
• W2259086253 hasConceptScore W2259086253C104317684 @default.
• W2259086253 hasConceptScore W2259086253C105580179 @default.
• W2259086253 hasConceptScore W2259086253C111936080 @default.
• W2259086253 hasConceptScore W2259086253C138885662 @default.
• W2259086253 hasConceptScore W2259086253C143141573 @default.
• W2259086253 hasConceptScore W2259086253C147789679 @default.
• W2259086253 hasConceptScore W2259086253C150194340 @default.
• W2259086253 hasConceptScore W2259086253C153911025 @default.
• W2259086253 hasConceptScore W2259086253C176990463 @default.
• W2259086253 hasConceptScore W2259086253C179926584 @default.
• W2259086253 hasConceptScore W2259086253C185592680 @default.
• W2259086253 hasConceptScore W2259086253C41895202 @default.
• W2259086253 hasConceptScore W2259086253C54009773 @default.
• W2259086253 hasConceptScore W2259086253C54355233 @default.
• W2259086253 hasConceptScore W2259086253C86339819 @default.
• W2259086253 hasConceptScore W2259086253C86803240 @default.
• W2259086253 hasConceptScore W2259086253C94671646 @default.
• W2259086253 hasLocation W22590862531 @default.
• W2259086253 hasLocation W22590862532 @default.
• W2259086253 hasOpenAccess W2259086253 @default.
• W2259086253 hasPrimaryLocation W22590862531 @default.

• next