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- W2259157440 abstract "Background. Radical lobectomy and pneumonectomy are the treatment of choice for most patients with lung cancer and have been traditionally thought to be the only chance for cure. However, limited resection is sometimes considered as a compromise in high-risk patients. Methods. We retrospectively reviewed our experiences in performing limited resections for patients with clinical T1 or T2 lung cancers who were poor surgical risks. Data were collected from 51 patients that received wedge (37 patients) or segmental (14 patients) resections due to either advanced age (35 patients were 70 years or older), poor pulmonary function (23 patients with FEV1 (forced expiratory volume in first second) equal to or less than 1.2 L) or concomitant serious diseases (24 patients). Results. No hospital deaths occurred but three patients had prolonged air leak after operations and two patients developed respiratory failure with good recovery using ventilator support. The follow-up period ranged from 0.5 to 4.9 years (median, 3.1 years). The 1-year, 2-year and 3-year survival rates were 91%, 76%, and 51%, respectively. The median survival time of patients met one, tow, or three criteria of high-risk factors were 36.0, 34.9, and 32.8 months, respectively (p=0.4231). Recurrence of disease developed in 21 (41%) of 51 patients. Five patients (10%) had local recurrence along; 13(26%) had distant metastasis alone; while three (6%) had both local recurrence and distant metastasis. Conclusions. Limited resection in selected high-risk patients with lung cancer may achieve acceptable operative mortality (0%) and morbidity rates (9.8%), however, both local (9.8%) and distal metastasis (31.4%) rates seemed relatively high and the long-term survival needs further evaluation." @default.
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- W2259157440 date "2000-09-01" @default.
- W2259157440 modified "2023-09-27" @default.
- W2259157440 title "Limited Resection for Lung Cancer in High-Risk Patients" @default.
- W2259157440 doi "https://doi.org/10.6558/mtjm.2000.5(3).4" @default.
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