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- W2259433062 abstract "Ferritin is a protein that playa a very important role in the storage of iron in the body. Ferritin is now emerging as a very important factor in the pathogenesis of diseases such as atherosclerosis , cancer , neuropsychiatric disorders to name a few. A number of mechanisms such as pro oxidant and pro inflammatory pathways are responsible for this. Ferritin performs diverse functions in the body besides iron storage. Alterations in the structure and concentration of ferritin have been observed in various diseases, establishing it as an important marker. The present review aims to understand the mechanisms involved in the cyto toxicity of iron and discuss some important disorders in which ferritin has emerged as an important bio marker. As ferritin has been established as a etiological factor in several disorders: pharmacological interventions to reduce its levels may prove beneficial . Indeed iron chelation therapy has been tried in various cancers with promising results. FERRITIN : A MULTIDIMENSIONAL BIOMARKER Ferritin and iron homeostasis have been implicated in the pathogenesis of many diseases, including disease involved in iron absorption transport and storage, atherosclerosis, cancer ,neuropsychiatric disorders and diabetes ." @default.
- W2259433062 created "2016-06-24" @default.
- W2259433062 date "2009-01-01" @default.
- W2259433062 modified "2023-09-26" @default.
- W2259433062 title "Ferritin: A multidimensional bio marker" @default.
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- W2259433062 doi "https://doi.org/10.5580/23e0" @default.
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