Matches in SemOpenAlex for { <https://semopenalex.org/work/W2259443180> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2259443180 abstract "Gd(III) is the paramagnetic metal ion most used for the preparation of contrast agents for magnetic resonance imaging, nevertheless Mn(II) can also be used [1]. So far there is only one FDA approved manganese-based contrast agent (Telascan) [2], in which the Mn(II) ion is slowly released in the tissues and the contrast observed is due to biomolecules-associated Mn(II). In this work we present a new ligand (NODAHep = 1,4,7-triazacyclononane-N,N’-acetic acid-N’’-heptane) for Mn(II). NODAHep is pentadentate, leaving one coordination site in the Mn(II) inner-sphere for a water molecule, and displays an alkylic side chain designed to make the chelate amphiphilic, increasing the rotational correlation time and consequently enhancing the chelate relaxivity [3]. The cmc of the chelate was determined by fluorescence using ANS (8-Anilinonaphthalene-1-sulfonate) as probe. The relaxivity of the chelate was measured at 20 MHz in the presence and absence of bovine serum albumin. The pH and temperature dependence of the relaxivity was also studied. The stability of the chelate in the presence of Zn(II) was investigated through relaxivity measurements." @default.
- W2259443180 created "2016-06-24" @default.
- W2259443180 creator A5037161471 @default.
- W2259443180 creator A5074025182 @default.
- W2259443180 creator A5089082217 @default.
- W2259443180 date "2011-09-01" @default.
- W2259443180 modified "2023-09-27" @default.
- W2259443180 title "NODAHep: a new triaza dicarboxylic chelator for manganese(II)" @default.
- W2259443180 hasPublicationYear "2011" @default.
- W2259443180 type Work @default.
- W2259443180 sameAs 2259443180 @default.
- W2259443180 citedByCount "0" @default.
- W2259443180 crossrefType "journal-article" @default.
- W2259443180 hasAuthorship W2259443180A5037161471 @default.
- W2259443180 hasAuthorship W2259443180A5074025182 @default.
- W2259443180 hasAuthorship W2259443180A5089082217 @default.
- W2259443180 hasConcept C11111787 @default.
- W2259443180 hasConcept C116569031 @default.
- W2259443180 hasConcept C121332964 @default.
- W2259443180 hasConcept C124712363 @default.
- W2259443180 hasConcept C170493617 @default.
- W2259443180 hasConcept C178790620 @default.
- W2259443180 hasConcept C179104552 @default.
- W2259443180 hasConcept C185592680 @default.
- W2259443180 hasConcept C197404232 @default.
- W2259443180 hasConcept C199164860 @default.
- W2259443180 hasConcept C32909587 @default.
- W2259443180 hasConcept C528890316 @default.
- W2259443180 hasConcept C544153396 @default.
- W2259443180 hasConcept C55493867 @default.
- W2259443180 hasConcept C557651011 @default.
- W2259443180 hasConcept C62520636 @default.
- W2259443180 hasConceptScore W2259443180C11111787 @default.
- W2259443180 hasConceptScore W2259443180C116569031 @default.
- W2259443180 hasConceptScore W2259443180C121332964 @default.
- W2259443180 hasConceptScore W2259443180C124712363 @default.
- W2259443180 hasConceptScore W2259443180C170493617 @default.
- W2259443180 hasConceptScore W2259443180C178790620 @default.
- W2259443180 hasConceptScore W2259443180C179104552 @default.
- W2259443180 hasConceptScore W2259443180C185592680 @default.
- W2259443180 hasConceptScore W2259443180C197404232 @default.
- W2259443180 hasConceptScore W2259443180C199164860 @default.
- W2259443180 hasConceptScore W2259443180C32909587 @default.
- W2259443180 hasConceptScore W2259443180C528890316 @default.
- W2259443180 hasConceptScore W2259443180C544153396 @default.
- W2259443180 hasConceptScore W2259443180C55493867 @default.
- W2259443180 hasConceptScore W2259443180C557651011 @default.
- W2259443180 hasConceptScore W2259443180C62520636 @default.
- W2259443180 hasLocation W22594431801 @default.
- W2259443180 hasOpenAccess W2259443180 @default.
- W2259443180 hasPrimaryLocation W22594431801 @default.
- W2259443180 hasRelatedWork W1971878016 @default.
- W2259443180 hasRelatedWork W1979470683 @default.
- W2259443180 hasRelatedWork W1996614923 @default.
- W2259443180 hasRelatedWork W2002824873 @default.
- W2259443180 hasRelatedWork W2007066308 @default.
- W2259443180 hasRelatedWork W2007959364 @default.
- W2259443180 hasRelatedWork W2041051033 @default.
- W2259443180 hasRelatedWork W2045322912 @default.
- W2259443180 hasRelatedWork W2059678247 @default.
- W2259443180 hasRelatedWork W2119670865 @default.
- W2259443180 hasRelatedWork W2131921381 @default.
- W2259443180 hasRelatedWork W2146063337 @default.
- W2259443180 hasRelatedWork W2153269379 @default.
- W2259443180 hasRelatedWork W2325943049 @default.
- W2259443180 hasRelatedWork W2790803647 @default.
- W2259443180 hasRelatedWork W2999425131 @default.
- W2259443180 hasRelatedWork W3133823065 @default.
- W2259443180 hasRelatedWork W437426778 @default.
- W2259443180 hasRelatedWork W658157047 @default.
- W2259443180 hasRelatedWork W2272599911 @default.
- W2259443180 isParatext "false" @default.
- W2259443180 isRetracted "false" @default.
- W2259443180 magId "2259443180" @default.
- W2259443180 workType "article" @default.