Matches in SemOpenAlex for { <https://semopenalex.org/work/W2259477029> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2259477029 abstract "Background: It is known that hypokalemia, hypocalcemia and hypomagnesemia cause a prolonged QTc interval and are associated with an increased risk of ventricular arrhythmias. However, there are limited data on optimal serum electrolytes for patients admitted to the coronary care unit (CCU). Objective: Here, we aimed to evaluate the relationship between serum potassium, ionized calcium and magnesium levels and in-hospital mortality in the CCU setting. Methods: This retrospective cohort study included 8,498 consecutive patients admitted to the CCU at an academic tertiary medical center from 2004 through 2013. The mean of serum electrolytes was categorized as <3.5, 3.5-<4.0, 4.0-<4.5 (reference), 4.5-<5.0, and ≥5.0 mEq/L for potassium; <4.4, 4.4-<4.6, 4.6-<4.8, 4.8-<5.0 (reference), and ≥5.0 mg/dL for ionized calcium; and <1.8, 1.8-<2.0, 2.0-<2.2 (reference), 2.2-<2.4, and ≥2.4 mg/dL for magnesium. Multivariate logistic regression analysis was used to determine the association between the mean of serum electrolytes and in-hospital mortality. Results: Of the 8,498 patients, 599 (7%) died during hospitalization. Relationship between mean serum potassium (U-shaped), ionized calcium (inverted J-shape) and magnesium (J-shaped) and in-hospital mortality was present in Figure. Serum potassium levels <3.5, 4.5-<5.0 and ≥5.0 mEq/L were independently associated with an increased risk of in-hospital mortality (adjusted OR 1.7 95% CI 1.1-2.5, OR 1.7 95% CI 1.3-2.2, and OR 3.4 95% CI 2.4-4.8, respectively), compared to the reference group. As for serum ionized calcium, the levels of <4.4, 4.4-<4.6, and 4.6-<4.8 mg/dL independently increased risk of mortality (adjusted OR 3.0 95% CI 2.3-4.0, OR 2.0 95% CI 1.5-2.6, and OR 1.4 95% CI, 1.1-1.8, respectively). As for serum magnesium, an only level above 2.4 mg/dL was associated with an increased mortality risk (OR 1.6 95% CI, 1.1-2.2). Conclusions: In the CCU setting, serum potassium 3.5-<4.5 mEq/L, ionized calcium ≥5.0 mg/dL and magnesium <2.4 mg/dL are associated with the lowest in-hospital mortality. These findings do not support supratherapeutic repletion of potassium and magnesium." @default.
- W2259477029 created "2016-06-24" @default.
- W2259477029 creator A5005027192 @default.
- W2259477029 creator A5010475216 @default.
- W2259477029 creator A5024567376 @default.
- W2259477029 creator A5024752712 @default.
- W2259477029 creator A5031186058 @default.
- W2259477029 creator A5040584995 @default.
- W2259477029 creator A5044514674 @default.
- W2259477029 creator A5045146592 @default.
- W2259477029 creator A5048715234 @default.
- W2259477029 creator A5053087229 @default.
- W2259477029 creator A5056467074 @default.
- W2259477029 creator A5057735964 @default.
- W2259477029 creator A5079546501 @default.
- W2259477029 date "2015-05-01" @default.
- W2259477029 modified "2023-10-16" @default.
- W2259477029 title "Abstract 344: Optimal Serum Potassium, Calcium and Magnesium in the Coronary Care Unit" @default.
- W2259477029 doi "https://doi.org/10.1161/circoutcomes.8.suppl_2.344" @default.
- W2259477029 hasPublicationYear "2015" @default.
- W2259477029 type Work @default.
- W2259477029 sameAs 2259477029 @default.
- W2259477029 citedByCount "0" @default.
- W2259477029 crossrefType "journal-article" @default.
- W2259477029 hasAuthorship W2259477029A5005027192 @default.
- W2259477029 hasAuthorship W2259477029A5010475216 @default.
- W2259477029 hasAuthorship W2259477029A5024567376 @default.
- W2259477029 hasAuthorship W2259477029A5024752712 @default.
- W2259477029 hasAuthorship W2259477029A5031186058 @default.
- W2259477029 hasAuthorship W2259477029A5040584995 @default.
- W2259477029 hasAuthorship W2259477029A5044514674 @default.
- W2259477029 hasAuthorship W2259477029A5045146592 @default.
- W2259477029 hasAuthorship W2259477029A5048715234 @default.
- W2259477029 hasAuthorship W2259477029A5053087229 @default.
- W2259477029 hasAuthorship W2259477029A5056467074 @default.
- W2259477029 hasAuthorship W2259477029A5057735964 @default.
- W2259477029 hasAuthorship W2259477029A5079546501 @default.
- W2259477029 hasConcept C126322002 @default.
- W2259477029 hasConcept C178790620 @default.
- W2259477029 hasConcept C185592680 @default.
- W2259477029 hasConcept C2776183862 @default.
- W2259477029 hasConcept C2777260377 @default.
- W2259477029 hasConcept C2778242168 @default.
- W2259477029 hasConcept C500558357 @default.
- W2259477029 hasConcept C517785266 @default.
- W2259477029 hasConcept C519063684 @default.
- W2259477029 hasConcept C543218039 @default.
- W2259477029 hasConcept C71924100 @default.
- W2259477029 hasConcept C72563966 @default.
- W2259477029 hasConcept C87975464 @default.
- W2259477029 hasConcept C90924648 @default.
- W2259477029 hasConceptScore W2259477029C126322002 @default.
- W2259477029 hasConceptScore W2259477029C178790620 @default.
- W2259477029 hasConceptScore W2259477029C185592680 @default.
- W2259477029 hasConceptScore W2259477029C2776183862 @default.
- W2259477029 hasConceptScore W2259477029C2777260377 @default.
- W2259477029 hasConceptScore W2259477029C2778242168 @default.
- W2259477029 hasConceptScore W2259477029C500558357 @default.
- W2259477029 hasConceptScore W2259477029C517785266 @default.
- W2259477029 hasConceptScore W2259477029C519063684 @default.
- W2259477029 hasConceptScore W2259477029C543218039 @default.
- W2259477029 hasConceptScore W2259477029C71924100 @default.
- W2259477029 hasConceptScore W2259477029C72563966 @default.
- W2259477029 hasConceptScore W2259477029C87975464 @default.
- W2259477029 hasConceptScore W2259477029C90924648 @default.
- W2259477029 hasIssue "suppl_2" @default.
- W2259477029 hasLocation W22594770291 @default.
- W2259477029 hasOpenAccess W2259477029 @default.
- W2259477029 hasPrimaryLocation W22594770291 @default.
- W2259477029 hasRelatedWork W1595204743 @default.
- W2259477029 hasRelatedWork W1972971875 @default.
- W2259477029 hasRelatedWork W1987311450 @default.
- W2259477029 hasRelatedWork W2004886252 @default.
- W2259477029 hasRelatedWork W2023562918 @default.
- W2259477029 hasRelatedWork W2023653541 @default.
- W2259477029 hasRelatedWork W2048633015 @default.
- W2259477029 hasRelatedWork W2160737953 @default.
- W2259477029 hasRelatedWork W2406036456 @default.
- W2259477029 hasRelatedWork W2463826646 @default.
- W2259477029 hasVolume "8" @default.
- W2259477029 isParatext "false" @default.
- W2259477029 isRetracted "false" @default.
- W2259477029 magId "2259477029" @default.
- W2259477029 workType "article" @default.