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- W2259510040 endingPage "837" @default.
- W2259510040 startingPage "831" @default.
- W2259510040 abstract "Childhood obesity jeopardizes a healthy future for our society's children as it is associated with increased cardiovascular morbidity and mortality later on in life. Endothelial dysfunction, the first step in the development of atherosclerosis, is already present in obese children and may well represent a targetable risk factor. Technological advancements in recent years have facilitated noninvasive measurements of endothelial homeostasis in children. Thereby this topic ultimately starts to get the attention it deserves. In this paper, we aim to summarize the latest insights on endothelial dysfunction in childhood obesity. We discuss methodological advancements in peripheral endothelial function measurement and newly identified diagnostic markers of vascular homeostasis. Finally, future challenges and perspectives are set forth on how to efficiently tackle the catastrophic rise in cardiovascular morbidity and mortality that will be inflicted on obese children if they are not treated optimally." @default.
- W2259510040 created "2016-06-24" @default.
- W2259510040 creator A5003871726 @default.
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- W2259510040 creator A5018295134 @default.
- W2259510040 creator A5028757696 @default.
- W2259510040 creator A5064089040 @default.
- W2259510040 date "2016-02-11" @default.
- W2259510040 modified "2023-10-10" @default.
- W2259510040 title "Childhood obesity–related endothelial dysfunction: an update on pathophysiological mechanisms and diagnostic advancements" @default.
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