Matches in SemOpenAlex for { <https://semopenalex.org/work/W2259653456> ?p ?o ?g. }
- W2259653456 endingPage "e0149063" @default.
- W2259653456 startingPage "e0149063" @default.
- W2259653456 abstract "Although the toxicity of melamine to the kidneys and testes is well known, few studies have investigated the effects of melamine on female reproductive organs. Therefore, this study explores the effects of oral administration melamine or melamine and cyanuric acid for 28 days on the ovaries of female rats. Rats that were exposed to the mixture exhibited reduced ovarian and uterine weights, a shorter estrous cycle, and reduced serum estrogen and progesterone levels compared to rats that were exposed to melamine and control rats. Furthermore, morphological analysis revealed pathological changes in the ovaries of rats exposed to melamine or the mixture, such as more atretic follicles and necrosis of oocytes and granulosa cells. TUNEL staining revealed that the exposed groups had a higher proportion of TUNEL-positive granulosa cells than the control group, and the mRNA expressions of SOD1, GPX1, GPX2, P450scc, 17β-HSD I, and 17β-HSD II were reduced in the exposure groups compared with the control group. These results indicated that exposure to melamine alone or to the melamine-cyanuric acid mixture could damage the ovaries in rats." @default.
- W2259653456 created "2016-06-24" @default.
- W2259653456 creator A5014177100 @default.
- W2259653456 creator A5061540041 @default.
- W2259653456 creator A5068041418 @default.
- W2259653456 creator A5073409941 @default.
- W2259653456 creator A5074919815 @default.
- W2259653456 creator A5088266408 @default.
- W2259653456 date "2016-02-11" @default.
- W2259653456 modified "2023-10-16" @default.
- W2259653456 title "Ovarian Toxicity in Female Rats after Oral Administration of Melamine or Melamine and Cyanuric Acid" @default.
- W2259653456 cites W1570662722 @default.
- W2259653456 cites W1964059310 @default.
- W2259653456 cites W1964739881 @default.
- W2259653456 cites W1974053942 @default.
- W2259653456 cites W1977741021 @default.
- W2259653456 cites W1978735816 @default.
- W2259653456 cites W1980460919 @default.
- W2259653456 cites W1985191673 @default.
- W2259653456 cites W1986821460 @default.
- W2259653456 cites W1991901423 @default.
- W2259653456 cites W1998401708 @default.
- W2259653456 cites W2008780802 @default.
- W2259653456 cites W2011781192 @default.
- W2259653456 cites W2015522428 @default.
- W2259653456 cites W2032992371 @default.
- W2259653456 cites W2042693666 @default.
- W2259653456 cites W2052229909 @default.
- W2259653456 cites W2057490006 @default.
- W2259653456 cites W2062257210 @default.
- W2259653456 cites W2070494545 @default.
- W2259653456 cites W2081832322 @default.
- W2259653456 cites W2085188058 @default.
- W2259653456 cites W2087790613 @default.
- W2259653456 cites W2106188053 @default.
- W2259653456 cites W2114508349 @default.
- W2259653456 cites W2120530839 @default.
- W2259653456 cites W2127382664 @default.
- W2259653456 cites W2137514647 @default.
- W2259653456 cites W2138818297 @default.
- W2259653456 cites W2146953761 @default.
- W2259653456 cites W2147322409 @default.
- W2259653456 cites W2151036905 @default.
- W2259653456 cites W2154048516 @default.
- W2259653456 cites W2168505600 @default.
- W2259653456 cites W2170597525 @default.
- W2259653456 cites W2224399614 @default.
- W2259653456 cites W3191898104 @default.
- W2259653456 doi "https://doi.org/10.1371/journal.pone.0149063" @default.
- W2259653456 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4750994" @default.
- W2259653456 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26866683" @default.
- W2259653456 hasPublicationYear "2016" @default.
- W2259653456 type Work @default.
- W2259653456 sameAs 2259653456 @default.
- W2259653456 citedByCount "16" @default.
- W2259653456 countsByYear W22596534562016 @default.
- W2259653456 countsByYear W22596534562017 @default.
- W2259653456 countsByYear W22596534562018 @default.
- W2259653456 countsByYear W22596534562019 @default.
- W2259653456 countsByYear W22596534562020 @default.
- W2259653456 countsByYear W22596534562021 @default.
- W2259653456 countsByYear W22596534562022 @default.
- W2259653456 countsByYear W22596534562023 @default.
- W2259653456 crossrefType "journal-article" @default.
- W2259653456 hasAuthorship W2259653456A5014177100 @default.
- W2259653456 hasAuthorship W2259653456A5061540041 @default.
- W2259653456 hasAuthorship W2259653456A5068041418 @default.
- W2259653456 hasAuthorship W2259653456A5073409941 @default.
- W2259653456 hasAuthorship W2259653456A5074919815 @default.
- W2259653456 hasAuthorship W2259653456A5088266408 @default.
- W2259653456 hasBestOaLocation W22596534561 @default.
- W2259653456 hasConcept C126322002 @default.
- W2259653456 hasConcept C134018914 @default.
- W2259653456 hasConcept C16685009 @default.
- W2259653456 hasConcept C178790620 @default.
- W2259653456 hasConcept C185592680 @default.
- W2259653456 hasConcept C190283241 @default.
- W2259653456 hasConcept C196795494 @default.
- W2259653456 hasConcept C2775979504 @default.
- W2259653456 hasConcept C2777683982 @default.
- W2259653456 hasConcept C2778206080 @default.
- W2259653456 hasConcept C29730261 @default.
- W2259653456 hasConcept C55493867 @default.
- W2259653456 hasConcept C71924100 @default.
- W2259653456 hasConcept C86803240 @default.
- W2259653456 hasConcept C99432707 @default.
- W2259653456 hasConceptScore W2259653456C126322002 @default.
- W2259653456 hasConceptScore W2259653456C134018914 @default.
- W2259653456 hasConceptScore W2259653456C16685009 @default.
- W2259653456 hasConceptScore W2259653456C178790620 @default.
- W2259653456 hasConceptScore W2259653456C185592680 @default.
- W2259653456 hasConceptScore W2259653456C190283241 @default.
- W2259653456 hasConceptScore W2259653456C196795494 @default.
- W2259653456 hasConceptScore W2259653456C2775979504 @default.
- W2259653456 hasConceptScore W2259653456C2777683982 @default.
- W2259653456 hasConceptScore W2259653456C2778206080 @default.
- W2259653456 hasConceptScore W2259653456C29730261 @default.
- W2259653456 hasConceptScore W2259653456C55493867 @default.