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• W2260690803 abstract "ObjectivesThis was a systematic review and meta-analysis to evaluate the incidence of adverse events in adults undergoing procedural sedation in the emergency department (ED).MethodsEight electronic databases were searched, including MEDLINE, EMBASE, EBSCO, CINAHL, CENTRAL, Cochrane Database of Systematic Reviews, Web of Science, and Scopus, from January 2005 through 2015. Randomized controlled trials and observational studies of adults undergoing procedural sedation in the ED that reported a priori selected outcomes and adverse events were included. Meta-analysis was performed using a random-effects model and reported as incidence rates with 95% confidence intervals (CIs).ResultsThe search yielded 2,046 titles for review. Fifty-five articles were eligible, including 9,652 procedural sedations. The most common adverse event was hypoxia, with an incidence of 40.2 per 1,000 sedations (95% CI = 32.5 to 47.9), followed by vomiting with 16.4 per 1,000 sedations (95% CI = 9.7 to 23.0) and hypotension with 15.2 per 1,000 sedations (95% CI = 10.7 to 19.7). Severe adverse events requiring emergent medical intervention were rare, with one case of aspiration in 2,370 sedations (1.2 per 1,000), one case of laryngospasm in 883 sedations (4.2 per 1,000), and two intubations in 3,636 sedations (1.6 per 1,000). The incidence of agitation and vomiting were higher with ketamine (164.1 per 1,000 and 170.0 per 1,000, respectively). Apnea was more frequent with midazolam (51.4 per 1,000), and hypoxia was less frequent in patients who received ketamine/propofol compared to other combinations. The case of laryngospasm was in a patient who received ketamine, and the aspiration and intubations were in patients who received propofol. When propofol and ketamine are combined, the incidences of agitation, apnea, hypoxia, bradycardia, hypotension, and vomiting were lower compared to each medication separately.ConclusionsSerious adverse events during procedural sedation like laryngospasm, aspiration, and intubation are exceedingly rare. Quantitative risk estimates are provided to facilitate shared decision-making, risk communication, and informed consent." @default.
• W2260690803 created "2016-06-24" @default.
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• W2260690803 date "2016-01-22" @default.
• W2260690803 modified "2023-10-18" @default.
• W2260690803 title "Incidence of Adverse Events in Adults Undergoing Procedural Sedation in the Emergency Department: A Systematic Review and Meta‐analysis" @default.
• W2260690803 cites W1492983089 @default.
• W2260690803 cites W1524648117 @default.
• W2260690803 cites W1589891294 @default.
• W2260690803 cites W1607123589 @default.
• W2260690803 cites W1926005564 @default.
• W2260690803 cites W1929945502 @default.
• W2260690803 cites W1949708446 @default.
• W2260690803 cites W1963887407 @default.
• W2260690803 cites W1965062688 @default.
• W2260690803 cites W1970092514 @default.
• W2260690803 cites W1975792880 @default.
• W2260690803 cites W1978407699 @default.
• W2260690803 cites W1992344412 @default.
• W2260690803 cites W1994017467 @default.
• W2260690803 cites W1996776758 @default.
• W2260690803 cites W2000924331 @default.
• W2260690803 cites W2002625617 @default.
• W2260690803 cites W2003931689 @default.
• W2260690803 cites W2004719041 @default.
• W2260690803 cites W2010081839 @default.
• W2260690803 cites W2014693538 @default.
• W2260690803 cites W2020720953 @default.
• W2260690803 cites W2023858507 @default.
• W2260690803 cites W2030866261 @default.
• W2260690803 cites W2031531734 @default.
• W2260690803 cites W2033900374 @default.
• W2260690803 cites W2036912855 @default.
• W2260690803 cites W2039189773 @default.
• W2260690803 cites W2041906662 @default.
• W2260690803 cites W2050666527 @default.
• W2260690803 cites W2052328284 @default.
• W2260690803 cites W2054465297 @default.
• W2260690803 cites W2056315306 @default.
• W2260690803 cites W2058903059 @default.
• W2260690803 cites W2059129352 @default.
• W2260690803 cites W2064668473 @default.
• W2260690803 cites W2065394800 @default.
• W2260690803 cites W2065688518 @default.
• W2260690803 cites W2067026957 @default.
• W2260690803 cites W2070404538 @default.
• W2260690803 cites W2083041419 @default.
• W2260690803 cites W2084089920 @default.
• W2260690803 cites W2086103904 @default.
• W2260690803 cites W2086974927 @default.
• W2260690803 cites W2087995002 @default.
• W2260690803 cites W2091599295 @default.
• W2260690803 cites W2094600158 @default.
• W2260690803 cites W2095304544 @default.
• W2260690803 cites W2105687746 @default.
• W2260690803 cites W2115211659 @default.
• W2260690803 cites W2118630816 @default.
• W2260690803 cites W2119051192 @default.
• W2260690803 cites W2120771911 @default.
• W2260690803 cites W2123296629 @default.
• W2260690803 cites W2133741786 @default.
• W2260690803 cites W2134476019 @default.
• W2260690803 cites W2134920783 @default.
• W2260690803 cites W2138487631 @default.
• W2260690803 cites W2139025733 @default.
• W2260690803 cites W2139580351 @default.
• W2260690803 cites W2143637052 @default.
• W2260690803 cites W2150342049 @default.
• W2260690803 cites W2152684425 @default.
• W2260690803 cites W2156098321 @default.
• W2260690803 cites W2158597963 @default.
• W2260690803 cites W2161925143 @default.
• W2260690803 cites W2162445884 @default.
• W2260690803 cites W2164328937 @default.
• W2260690803 cites W2164374174 @default.
• W2260690803 cites W2167952600 @default.
• W2260690803 cites W2182947919 @default.
• W2260690803 cites W2272855132 @default.
• W2260690803 cites W2327923767 @default.
• W2260690803 cites W2334563999 @default.
• W2260690803 cites W2775188175 @default.
• W2260690803 cites W2991792334 @default.
• W2260690803 cites W4241719573 @default.
• W2260690803 cites W4243263960 @default.
• W2260690803 cites W4253096148 @default.
• W2260690803 cites W4361868505 @default.
• W2260690803 doi "https://doi.org/10.1111/acem.12875" @default.
• W2260690803 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4755157" @default.
• W2260690803 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26801209" @default.
• W2260690803 hasPublicationYear "2016" @default.
• W2260690803 type Work @default.

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