Matches in SemOpenAlex for { <https://semopenalex.org/work/W2260705557> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2260705557 endingPage "42" @default.
- W2260705557 startingPage "39" @default.
- W2260705557 abstract "Background : To explore the effect of single oral dose of esomeprazole 20 mg, administered a night before surgery, on intragastric pH and volume in adult patients undergoing elective surgery by excluding cases contaminated with duodenogastric refluxate.Patients and Methods : This prospective, triple blind, randomised and placebo controlled clinical trial was conducted to explore the effect of single oral dose of esomeprazole 20 mg, administered a night before surgery, on intragastric pH and volume on 120 adult inpatients of either sex, American Society of Anaesthesiologist physical status I-II, and aged 15-70 years. The patients in Group C (control) received placebo while Group E (Esomeprazole) received esomeprazole orally 9.00 pm, the night before elective surgery. On the day of surgery, the gastric contents were aspirated with a large bore, multi-orifice gastric tube passed through an endotracheal tube placed blindly in the oesophagus after tracheal intubation and analysed for pH, volume and the presence of bile salts.Results : Thirty nine samples (33%) out of 117 were contaminated with duodenal contents. Duodenogastric reflux significantly affected pH and volume in Group C (p value 0.0003 and 0.0016) and E (p value 0.0401 and < 0.0001). Esomeprazole, after excluding samples contaminated with duodenal fluid, significantly increased pH (p < 0.0001), decreased volume (p 0.0068) and the percentage of the patients (2.56% versus 30.76%) considered at risk compared with placebo (p 0.0015) according to the criteria defined (pH ≤ 2.5 and volume ≥ 25 ml).Conclusion : Esomeprazole 20 mg administered orally a night before elective surgery improved the gastric environment (pH 25 ml / kg) the time of induction of anaesthesia excluding samples contaminated with duodenogastric reflux." @default.
- W2260705557 created "2016-06-24" @default.
- W2260705557 creator A5031852100 @default.
- W2260705557 creator A5080316258 @default.
- W2260705557 creator A5082706421 @default.
- W2260705557 date "2008-09-01" @default.
- W2260705557 modified "2023-09-24" @default.
- W2260705557 title "Esomeprazole as a prophylactic agent for acid aspiration syndrome in adult patients undergoing elective surgery : a triple blind placebo controlled clinical trial : original research" @default.
- W2260705557 hasPublicationYear "2008" @default.
- W2260705557 type Work @default.
- W2260705557 sameAs 2260705557 @default.
- W2260705557 citedByCount "0" @default.
- W2260705557 crossrefType "journal-article" @default.
- W2260705557 hasAuthorship W2260705557A5031852100 @default.
- W2260705557 hasAuthorship W2260705557A5080316258 @default.
- W2260705557 hasAuthorship W2260705557A5082706421 @default.
- W2260705557 hasConcept C126322002 @default.
- W2260705557 hasConcept C141071460 @default.
- W2260705557 hasConcept C142724271 @default.
- W2260705557 hasConcept C168563851 @default.
- W2260705557 hasConcept C185592680 @default.
- W2260705557 hasConcept C204787440 @default.
- W2260705557 hasConcept C27081682 @default.
- W2260705557 hasConcept C2777963132 @default.
- W2260705557 hasConcept C2778204628 @default.
- W2260705557 hasConcept C2778716859 @default.
- W2260705557 hasConcept C2779134260 @default.
- W2260705557 hasConcept C2781025758 @default.
- W2260705557 hasConcept C2781312054 @default.
- W2260705557 hasConcept C3018292220 @default.
- W2260705557 hasConcept C42219234 @default.
- W2260705557 hasConcept C43270747 @default.
- W2260705557 hasConcept C43617362 @default.
- W2260705557 hasConcept C535046627 @default.
- W2260705557 hasConcept C71924100 @default.
- W2260705557 hasConcept C90924648 @default.
- W2260705557 hasConceptScore W2260705557C126322002 @default.
- W2260705557 hasConceptScore W2260705557C141071460 @default.
- W2260705557 hasConceptScore W2260705557C142724271 @default.
- W2260705557 hasConceptScore W2260705557C168563851 @default.
- W2260705557 hasConceptScore W2260705557C185592680 @default.
- W2260705557 hasConceptScore W2260705557C204787440 @default.
- W2260705557 hasConceptScore W2260705557C27081682 @default.
- W2260705557 hasConceptScore W2260705557C2777963132 @default.
- W2260705557 hasConceptScore W2260705557C2778204628 @default.
- W2260705557 hasConceptScore W2260705557C2778716859 @default.
- W2260705557 hasConceptScore W2260705557C2779134260 @default.
- W2260705557 hasConceptScore W2260705557C2781025758 @default.
- W2260705557 hasConceptScore W2260705557C2781312054 @default.
- W2260705557 hasConceptScore W2260705557C3018292220 @default.
- W2260705557 hasConceptScore W2260705557C42219234 @default.
- W2260705557 hasConceptScore W2260705557C43270747 @default.
- W2260705557 hasConceptScore W2260705557C43617362 @default.
- W2260705557 hasConceptScore W2260705557C535046627 @default.
- W2260705557 hasConceptScore W2260705557C71924100 @default.
- W2260705557 hasConceptScore W2260705557C90924648 @default.
- W2260705557 hasIssue "5" @default.
- W2260705557 hasLocation W22607055571 @default.
- W2260705557 hasOpenAccess W2260705557 @default.
- W2260705557 hasPrimaryLocation W22607055571 @default.
- W2260705557 hasRelatedWork W1947053410 @default.
- W2260705557 hasRelatedWork W1981343916 @default.
- W2260705557 hasRelatedWork W1983550640 @default.
- W2260705557 hasRelatedWork W1990921533 @default.
- W2260705557 hasRelatedWork W1996370250 @default.
- W2260705557 hasRelatedWork W2018519246 @default.
- W2260705557 hasRelatedWork W2023050415 @default.
- W2260705557 hasRelatedWork W2037290396 @default.
- W2260705557 hasRelatedWork W2048150275 @default.
- W2260705557 hasRelatedWork W2067883760 @default.
- W2260705557 hasRelatedWork W2068503885 @default.
- W2260705557 hasRelatedWork W2121277627 @default.
- W2260705557 hasRelatedWork W2124285328 @default.
- W2260705557 hasRelatedWork W2127755595 @default.
- W2260705557 hasRelatedWork W2134460826 @default.
- W2260705557 hasRelatedWork W2313159397 @default.
- W2260705557 hasRelatedWork W2389626421 @default.
- W2260705557 hasRelatedWork W2401197138 @default.
- W2260705557 hasRelatedWork W2471762316 @default.
- W2260705557 hasRelatedWork W2739809644 @default.
- W2260705557 hasVolume "14" @default.
- W2260705557 isParatext "false" @default.
- W2260705557 isRetracted "false" @default.
- W2260705557 magId "2260705557" @default.
- W2260705557 workType "article" @default.