Matches in SemOpenAlex for { <https://semopenalex.org/work/W2260906944> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2260906944 abstract "Sodium valproate, a broad spectrum antiepileptic elevates the brain GABA levels by various mechanisms. Histological, electrophysiological and the biochemical studies suggest a regulatory role of GABA on dopaminergic neurons. Behavioral studies in animals provide an additional evidence for interaction between GABAergic and DAergic systems. Valproate at 200-500mg/kg induces Wet Dog Shake (WDS) behavior in rats. The WDS behavior in rats and head twitch responses in mice is evoked by 5- hydroxy-tryptophan (5-HT), the 5-HT precursor, the directly acting non-selective 5-HT receptor agonists and 5-HT releasers. In order to determine the involvement of GABAergic and 5-HTergic mechanism in the induction of WDS behavior by valproate in rats, the study was taken upto investigate the effect picrotoxin and cyproheptadine pretreatment on valproate induced WDS in rats. It was observed that subconvulsant doses of picrotoxin failed to antagonize valproate induced WDS while cyproheptadine effectively antagonized valproate induced WDS behavior in rats. Based on our study we propose that GABAergic and 5-HTergic systems are involved in production and controlling WDS behavior evoked by valproate in rats." @default.
- W2260906944 created "2016-06-24" @default.
- W2260906944 creator A5020688856 @default.
- W2260906944 creator A5071756151 @default.
- W2260906944 creator A5086422208 @default.
- W2260906944 date "2012-05-01" @default.
- W2260906944 modified "2023-09-26" @default.
- W2260906944 title "Effect of picrotoxin and cyproheptadine pretreatment on sodium valproate induced wet dog shake behavior in rats" @default.
- W2260906944 cites W1481021837 @default.
- W2260906944 cites W1772950163 @default.
- W2260906944 cites W1994862483 @default.
- W2260906944 cites W2005708482 @default.
- W2260906944 cites W2022798120 @default.
- W2260906944 cites W2038243857 @default.
- W2260906944 cites W2039829114 @default.
- W2260906944 cites W2059317623 @default.
- W2260906944 cites W2060172635 @default.
- W2260906944 cites W2066663898 @default.
- W2260906944 cites W2081490747 @default.
- W2260906944 hasPublicationYear "2012" @default.
- W2260906944 type Work @default.
- W2260906944 sameAs 2260906944 @default.
- W2260906944 citedByCount "0" @default.
- W2260906944 crossrefType "journal-article" @default.
- W2260906944 hasAuthorship W2260906944A5020688856 @default.
- W2260906944 hasAuthorship W2260906944A5071756151 @default.
- W2260906944 hasAuthorship W2260906944A5086422208 @default.
- W2260906944 hasConcept C126322002 @default.
- W2260906944 hasConcept C134018914 @default.
- W2260906944 hasConcept C137183658 @default.
- W2260906944 hasConcept C15744967 @default.
- W2260906944 hasConcept C168258287 @default.
- W2260906944 hasConcept C169760540 @default.
- W2260906944 hasConcept C170493617 @default.
- W2260906944 hasConcept C185592680 @default.
- W2260906944 hasConcept C2775858608 @default.
- W2260906944 hasConcept C2775864247 @default.
- W2260906944 hasConcept C2777172819 @default.
- W2260906944 hasConcept C2778186239 @default.
- W2260906944 hasConcept C2778206117 @default.
- W2260906944 hasConcept C2779177108 @default.
- W2260906944 hasConcept C2779324764 @default.
- W2260906944 hasConcept C37000724 @default.
- W2260906944 hasConcept C513476851 @default.
- W2260906944 hasConcept C71924100 @default.
- W2260906944 hasConcept C98274493 @default.
- W2260906944 hasConceptScore W2260906944C126322002 @default.
- W2260906944 hasConceptScore W2260906944C134018914 @default.
- W2260906944 hasConceptScore W2260906944C137183658 @default.
- W2260906944 hasConceptScore W2260906944C15744967 @default.
- W2260906944 hasConceptScore W2260906944C168258287 @default.
- W2260906944 hasConceptScore W2260906944C169760540 @default.
- W2260906944 hasConceptScore W2260906944C170493617 @default.
- W2260906944 hasConceptScore W2260906944C185592680 @default.
- W2260906944 hasConceptScore W2260906944C2775858608 @default.
- W2260906944 hasConceptScore W2260906944C2775864247 @default.
- W2260906944 hasConceptScore W2260906944C2777172819 @default.
- W2260906944 hasConceptScore W2260906944C2778186239 @default.
- W2260906944 hasConceptScore W2260906944C2778206117 @default.
- W2260906944 hasConceptScore W2260906944C2779177108 @default.
- W2260906944 hasConceptScore W2260906944C2779324764 @default.
- W2260906944 hasConceptScore W2260906944C37000724 @default.
- W2260906944 hasConceptScore W2260906944C513476851 @default.
- W2260906944 hasConceptScore W2260906944C71924100 @default.
- W2260906944 hasConceptScore W2260906944C98274493 @default.
- W2260906944 hasLocation W22609069441 @default.
- W2260906944 hasOpenAccess W2260906944 @default.
- W2260906944 hasPrimaryLocation W22609069441 @default.
- W2260906944 hasRelatedWork W1497696373 @default.
- W2260906944 hasRelatedWork W1924838430 @default.
- W2260906944 hasRelatedWork W1965098786 @default.
- W2260906944 hasRelatedWork W1980117682 @default.
- W2260906944 hasRelatedWork W1990301177 @default.
- W2260906944 hasRelatedWork W1993445380 @default.
- W2260906944 hasRelatedWork W2005356806 @default.
- W2260906944 hasRelatedWork W2022328122 @default.
- W2260906944 hasRelatedWork W2027903270 @default.
- W2260906944 hasRelatedWork W2029717667 @default.
- W2260906944 hasRelatedWork W2030980141 @default.
- W2260906944 hasRelatedWork W2036410559 @default.
- W2260906944 hasRelatedWork W2054731310 @default.
- W2260906944 hasRelatedWork W2055872879 @default.
- W2260906944 hasRelatedWork W2130203159 @default.
- W2260906944 hasRelatedWork W2415725533 @default.
- W2260906944 hasRelatedWork W2415907929 @default.
- W2260906944 hasRelatedWork W2438181233 @default.
- W2260906944 hasRelatedWork W3103138703 @default.
- W2260906944 hasRelatedWork W3189890545 @default.
- W2260906944 isParatext "false" @default.
- W2260906944 isRetracted "false" @default.
- W2260906944 magId "2260906944" @default.
- W2260906944 workType "article" @default.