Matches in SemOpenAlex for { <https://semopenalex.org/work/W2261014543> ?p ?o ?g. }
- W2261014543 endingPage "C973" @default.
- W2261014543 startingPage "C965" @default.
- W2261014543 abstract "The Hox gene family of transcription factors constitutes candidate regulators in the molecular cascade of events that governs establishment of normal terminal differentiation along the duodenum to colon axis. One member of this family, Hoxa5, displays a dynamic pattern of expression during gut development. Hoxa5 transcripts are present in midgut mesenchyme at the time of remodeling, supporting a role for this gene in digestive tract specification. To study the role of Hoxa5 in proper intestinal development and maturation, we examined whether Hoxa5 mutant mice exhibit any defect in this process. We report here that even though Hoxa5 is not required for midgut morphogenesis, its loss of function perturbs the acquisition of adult mode of digestion, which normally is temporally coordinated with the process of spontaneous weaning. Impaired maturation of the digestive tract might be related to altered specification of intestinal epithelial cells. Our findings provide evidence that Hoxa5 expression in the gut mesoderm is important for the region-specific differentiation of the adjacent endoderm." @default.
- W2261014543 created "2016-06-24" @default.
- W2261014543 creator A5070473236 @default.
- W2261014543 creator A5073838701 @default.
- W2261014543 creator A5076388980 @default.
- W2261014543 creator A5085607180 @default.
- W2261014543 date "1999-11-01" @default.
- W2261014543 modified "2023-10-18" @default.
- W2261014543 title "Loss of<i>Hoxa5</i>gene function in mice perturbs intestinal maturation" @default.
- W2261014543 cites W1500070160 @default.
- W2261014543 cites W1593098818 @default.
- W2261014543 cites W1775749144 @default.
- W2261014543 cites W1864480592 @default.
- W2261014543 cites W1873499297 @default.
- W2261014543 cites W1957995282 @default.
- W2261014543 cites W1966246416 @default.
- W2261014543 cites W1970620635 @default.
- W2261014543 cites W1983203736 @default.
- W2261014543 cites W1985665104 @default.
- W2261014543 cites W1990278701 @default.
- W2261014543 cites W1994734055 @default.
- W2261014543 cites W1996151007 @default.
- W2261014543 cites W1997071304 @default.
- W2261014543 cites W2002569113 @default.
- W2261014543 cites W2025468425 @default.
- W2261014543 cites W2028512158 @default.
- W2261014543 cites W2048249977 @default.
- W2261014543 cites W2049469517 @default.
- W2261014543 cites W2060929301 @default.
- W2261014543 cites W2063797944 @default.
- W2261014543 cites W2070567775 @default.
- W2261014543 cites W2077309447 @default.
- W2261014543 cites W2077331340 @default.
- W2261014543 cites W2081701445 @default.
- W2261014543 cites W2091987653 @default.
- W2261014543 cites W2093347136 @default.
- W2261014543 cites W2103300932 @default.
- W2261014543 cites W2104593931 @default.
- W2261014543 cites W2129679172 @default.
- W2261014543 cites W2133201173 @default.
- W2261014543 cites W2134894529 @default.
- W2261014543 cites W2135665041 @default.
- W2261014543 cites W2143426775 @default.
- W2261014543 cites W2145424250 @default.
- W2261014543 cites W2154721036 @default.
- W2261014543 cites W2155950685 @default.
- W2261014543 cites W2165386899 @default.
- W2261014543 cites W2178737721 @default.
- W2261014543 cites W313484932 @default.
- W2261014543 doi "https://doi.org/10.1152/ajpcell.1999.277.5.c965" @default.
- W2261014543 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10564089" @default.
- W2261014543 hasPublicationYear "1999" @default.
- W2261014543 type Work @default.
- W2261014543 sameAs 2261014543 @default.
- W2261014543 citedByCount "66" @default.
- W2261014543 countsByYear W22610145432012 @default.
- W2261014543 countsByYear W22610145432013 @default.
- W2261014543 countsByYear W22610145432014 @default.
- W2261014543 countsByYear W22610145432015 @default.
- W2261014543 countsByYear W22610145432016 @default.
- W2261014543 countsByYear W22610145432017 @default.
- W2261014543 countsByYear W22610145432018 @default.
- W2261014543 countsByYear W22610145432019 @default.
- W2261014543 countsByYear W22610145432020 @default.
- W2261014543 countsByYear W22610145432022 @default.
- W2261014543 countsByYear W22610145432023 @default.
- W2261014543 crossrefType "journal-article" @default.
- W2261014543 hasAuthorship W2261014543A5070473236 @default.
- W2261014543 hasAuthorship W2261014543A5073838701 @default.
- W2261014543 hasAuthorship W2261014543A5076388980 @default.
- W2261014543 hasAuthorship W2261014543A5085607180 @default.
- W2261014543 hasConcept C104317684 @default.
- W2261014543 hasConcept C111039654 @default.
- W2261014543 hasConcept C143065580 @default.
- W2261014543 hasConcept C145103041 @default.
- W2261014543 hasConcept C148738053 @default.
- W2261014543 hasConcept C196843134 @default.
- W2261014543 hasConcept C2776340970 @default.
- W2261014543 hasConcept C2777164004 @default.
- W2261014543 hasConcept C2780915607 @default.
- W2261014543 hasConcept C40692019 @default.
- W2261014543 hasConcept C54355233 @default.
- W2261014543 hasConcept C86339819 @default.
- W2261014543 hasConcept C86803240 @default.
- W2261014543 hasConcept C95444343 @default.
- W2261014543 hasConceptScore W2261014543C104317684 @default.
- W2261014543 hasConceptScore W2261014543C111039654 @default.
- W2261014543 hasConceptScore W2261014543C143065580 @default.
- W2261014543 hasConceptScore W2261014543C145103041 @default.
- W2261014543 hasConceptScore W2261014543C148738053 @default.
- W2261014543 hasConceptScore W2261014543C196843134 @default.
- W2261014543 hasConceptScore W2261014543C2776340970 @default.
- W2261014543 hasConceptScore W2261014543C2777164004 @default.
- W2261014543 hasConceptScore W2261014543C2780915607 @default.
- W2261014543 hasConceptScore W2261014543C40692019 @default.
- W2261014543 hasConceptScore W2261014543C54355233 @default.
- W2261014543 hasConceptScore W2261014543C86339819 @default.
- W2261014543 hasConceptScore W2261014543C86803240 @default.