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• W2261031738 startingPage "1445" @default.
• W2261031738 abstract "Wilms’ tumor is the most common renal tumor in children in which diffusely anaplastic or unfavorable histology foreshadows poor prognosis. MicroRNAs are small, non-coding RNAs that negatively regulate gene expression at the posttranscriptional level. Accumulating evidence shows that microRNA dysregulation takes part in the pathogenesis of many renal diseases, such as chronic kidney diseases, polycystic kidney disease, renal fibrosis, and renal cancers. In Wilms’ tumor, dysregulation of some key oncogenic or tumor-suppressing microRNAs, such as miR-17~92 cluster, miR-185, miR-204, and miR-483, has been documented. In this review, we will summarize current evidence on the role of dysregulated microRNAs in the development of Wilms’ tumor." @default.
• W2261031738 created "2016-06-24" @default.
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• W2261031738 creator A5056447268 @default.
• W2261031738 creator A5056975844 @default.
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• W2261031738 date "2015-12-03" @default.
• W2261031738 modified "2023-09-30" @default.
• W2261031738 title "The roles of microRNAs in Wilms’ tumors" @default.
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• W2261031738 doi "https://doi.org/10.1007/s13277-015-4514-8" @default.
• W2261031738 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26634744" @default.
• W2261031738 hasPublicationYear "2015" @default.
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