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• W2261303017 abstract "<h3>Importance</h3> Advances in mobile technology have resulted in federal and industry-level initiatives to facilitate large-scale clinical research using smart devices. Although the benefits of technology to expand data collection are obvious, assumptions about the reach of mobile research methods (<i>access</i>), participant willingness to engage in mobile research protocols (<i>engagement</i>), and the cost of this research (<i>cost</i>) remain untested. <h3>Objective</h3> To assess the feasibility of a fully mobile randomised controlled trial using assessments and treatments delivered entirely through mobile devices to depressed individuals. <h3>Design</h3> Using a web-based research portal, adult participants with depression who also owned a smart device were screened, consented and randomised to 1 of 3 mental health apps for treatment. Assessments of self-reported mood and cognitive function were conducted at baseline, 4, 8 and 12 weeks. Physical and social activity was monitored daily using passively collected phone use data. All treatment and assessment tools were housed on each participant9s smart phone or tablet. <h3>Interventions</h3> A cognitive training application, an application based on problem-solving therapy, and a mobile-sensing application promoting daily activities. <h3>Results</h3> <i>Access</i>: We screened 2923 people and enrolled 1098 participants in 5 months. The sample characteristics were comparable to the 2013 US census data. Recruitment via Craigslist.org yielded the largest sample. <i>Engagement</i>: Study engagement was high during the first 2 weeks of treatment, falling to 44% adherence by the 4th week. <i>Cost</i>: The total amount spent on for this project, including staff costs and β testing, was $314 264 over 2 years. <h3>Conclusions and relevance</h3> These findings suggest that mobile randomised control trials can recruit large numbers of participants in a short period of time and with minimal cost, but study engagement remains challenging. <h3>Trial registration number</h3> NCT00540865." @default.
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• W2261303017 date "2016-01-01" @default.
• W2261303017 modified "2023-10-16" @default.
• W2261303017 title "Conducting a fully mobile and randomised clinical trial for depression: access, engagement and expense" @default.
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• W2261303017 doi "https://doi.org/10.1136/bmjinnov-2015-000098" @default.
• W2261303017 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4789688" @default.
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