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• W2261445836 abstract "There is considerable evidence now that activity in retinal afferents plays an important role in the formation of connections between retinal ganglion cell axons and their target cells in the lateral geniculate nucleus (LGN). Thus, postnatal eyelid suture in kittens prevents retinogeniculate X and Y axon arbors from developing normally (Sur et al., 1982), and causes postsynaptic X and Y LGN cells to have abnormal structural and functional features (Friedlander et al., 1982; Sherman and Spear, 1982). Blocking action potentials in retinal afferents by infusing tetrodotoxin (TTX) intraocularly in postnatal kittens also alters the morphology of retinogeniculate axon arbors (Sur et al., 1985), and causes LGN cells to have abnormal physiological properties (Dubin et al., 1986). Infusion of TTX into the vicinity of the optic chiasm in prenatal kittens prevents the formation of eye-specific laminae (Shatz and Stryker, 1988), and causes retinogeniculate axon arbors to be abnormally large (Sretavan et al., 1988)." @default.
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• W2261445836 date "1992-01-01" @default.
• W2261445836 modified "2023-09-25" @default.
• W2261445836 title "Role of Postsynaptic Activity in Retinogeniculate Pattern Formation" @default.
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• W2261445836 doi "https://doi.org/10.1007/978-1-4899-6726-8_8" @default.
• W2261445836 hasPublicationYear "1992" @default.
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