FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2261484680> ?p ?o ?g. }

• W2261484680 abstract "The intestinal epithelium is an important barrier that depends on a complex mixture of proteins and these proteins comprise different intercellular junctions. The purpose of this study was to investigate the postnatal and developmental changes in morphology, intercellular junctions and voltage-gated potassium (Kv) channels in the intestine of piglets during the suckling and post-weaning periods.Samples of the small intestine were obtained from 1-, 7-, 14-, and 21-d-old suckling piglets and piglets on d 1, 3, 5, and 7 after weaning at 14 d of age. The results showed that the percentage of proliferating cell nuclear antigen (PCNA)-positive cells and alkaline phosphatase (AKP) activity, as well as the abundances of E-cadherin, occludin, and Kv1.5 mRNA and claudin-1, claudin-3, and occludin protein in the jejunum were increased from d 1 to d 21 during the suckling period (P < 0.05). Weaning induced decreases in the percentage of PCNA-positive cells, AKP activity and the abundances of E-cadherin, occludin and zonula occludens (ZO)-1 mRNA or protein in the jejunum on d 1, 3 and 5 post-weaning (P < 0.05). There were lower abundances of E-cadherin, occludin and ZO-1 mRNA as well as claudin-1, claudin-3 and ZO-1 protein in the jejunum of weanling piglets than in 21-d-old suckling piglets (P < 0.05). The abundances of E-cadherin, occludin, ZO-1 and integrin mRNA were positively related to the percentage of PCNA-positive cells.Weaning at 14 d of age induced damage to the intestinal morphology and barrier. While there was an adaptive restoration on d 7 post-weaning, the measured values did not return to the pre-weaning levels, which reflected the impairment of intercellular junctions and Kv channels." @default.
• W2261484680 created "2016-06-24" @default.
• W2261484680 creator A5006993178 @default.
• W2261484680 creator A5008929986 @default.
• W2261484680 creator A5031045584 @default.
• W2261484680 creator A5037677450 @default.
• W2261484680 creator A5038705360 @default.
• W2261484680 creator A5040013025 @default.
• W2261484680 creator A5053584037 @default.
• W2261484680 creator A5057584525 @default.
• W2261484680 creator A5066598571 @default.
• W2261484680 creator A5084874107 @default.
• W2261484680 date "2016-01-27" @default.
• W2261484680 modified "2023-10-14" @default.
• W2261484680 title "Developmental changes in intercellular junctions and Kv channels in the intestine of piglets during the suckling and post-weaning periods" @default.
• W2261484680 cites W142262936 @default.
• W2261484680 cites W165930648 @default.
• W2261484680 cites W1903344188 @default.
• W2261484680 cites W1931849508 @default.
• W2261484680 cites W1967956234 @default.
• W2261484680 cites W1971724873 @default.
• W2261484680 cites W1975549936 @default.
• W2261484680 cites W1981773624 @default.
• W2261484680 cites W1983687844 @default.
• W2261484680 cites W1989822344 @default.
• W2261484680 cites W2007120270 @default.
• W2261484680 cites W2011663421 @default.
• W2261484680 cites W2012882901 @default.
• W2261484680 cites W2014209146 @default.
• W2261484680 cites W2018815492 @default.
• W2261484680 cites W2020346975 @default.
• W2261484680 cites W2025839140 @default.
• W2261484680 cites W2027946879 @default.
• W2261484680 cites W2037338346 @default.
• W2261484680 cites W2050160216 @default.
• W2261484680 cites W2056700437 @default.
• W2261484680 cites W2056855417 @default.
• W2261484680 cites W2058778231 @default.
• W2261484680 cites W2064044310 @default.
• W2261484680 cites W2092107537 @default.
• W2261484680 cites W2097567512 @default.
• W2261484680 cites W2102688579 @default.
• W2261484680 cites W2102742338 @default.
• W2261484680 cites W2115321991 @default.
• W2261484680 cites W2117982300 @default.
• W2261484680 cites W2121962640 @default.
• W2261484680 cites W2127405306 @default.
• W2261484680 cites W2129003236 @default.
• W2261484680 cites W2134415362 @default.
• W2261484680 cites W2140932205 @default.
• W2261484680 cites W2148635587 @default.
• W2261484680 cites W2156868373 @default.
• W2261484680 cites W2158734604 @default.
• W2261484680 cites W2166263546 @default.
• W2261484680 cites W2168114680 @default.
• W2261484680 cites W2171262734 @default.
• W2261484680 cites W2187110352 @default.
• W2261484680 cites W2235416465 @default.
• W2261484680 cites W2345609573 @default.
• W2261484680 cites W2416556007 @default.
• W2261484680 cites W252986008 @default.
• W2261484680 cites W4247382314 @default.
• W2261484680 cites W71916131 @default.
• W2261484680 doi "https://doi.org/10.1186/s40104-016-0063-2" @default.
• W2261484680 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4729073" @default.
• W2261484680 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26819706" @default.
• W2261484680 hasPublicationYear "2016" @default.
• W2261484680 type Work @default.
• W2261484680 sameAs 2261484680 @default.
• W2261484680 citedByCount "49" @default.
• W2261484680 countsByYear W22614846802016 @default.
• W2261484680 countsByYear W22614846802017 @default.
• W2261484680 countsByYear W22614846802018 @default.
• W2261484680 countsByYear W22614846802019 @default.
• W2261484680 countsByYear W22614846802020 @default.
• W2261484680 countsByYear W22614846802021 @default.
• W2261484680 countsByYear W22614846802022 @default.
• W2261484680 countsByYear W22614846802023 @default.
• W2261484680 crossrefType "journal-article" @default.
• W2261484680 hasAuthorship W2261484680A5006993178 @default.
• W2261484680 hasAuthorship W2261484680A5008929986 @default.
• W2261484680 hasAuthorship W2261484680A5031045584 @default.
• W2261484680 hasAuthorship W2261484680A5037677450 @default.
• W2261484680 hasAuthorship W2261484680A5038705360 @default.
• W2261484680 hasAuthorship W2261484680A5040013025 @default.
• W2261484680 hasAuthorship W2261484680A5053584037 @default.
• W2261484680 hasAuthorship W2261484680A5057584525 @default.
• W2261484680 hasAuthorship W2261484680A5066598571 @default.
• W2261484680 hasAuthorship W2261484680A5084874107 @default.
• W2261484680 hasBestOaLocation W22614846801 @default.
• W2261484680 hasConcept C104317684 @default.
• W2261484680 hasConcept C105580179 @default.
• W2261484680 hasConcept C126322002 @default.
• W2261484680 hasConcept C134018914 @default.
• W2261484680 hasConcept C1491633281 @default.
• W2261484680 hasConcept C16685009 @default.
• W2261484680 hasConcept C177779419 @default.
• W2261484680 hasConcept C2775962179 @default.
• W2261484680 hasConcept C2776366702 @default.
• W2261484680 hasConcept C2777226302 @default.

• next