Matches in SemOpenAlex for { <https://semopenalex.org/work/W2261562213> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2261562213 endingPage "71" @default.
- W2261562213 startingPage "166" @default.
- W2261562213 abstract "Aspartic acid, cystine, methionine and tyrosine were protective against carbon tetrachloride (CCl4)-induced liver necrosis 24 h after its administration, when given 30 min before the hepatotoxin. Aspartic acid, cystine and tyrosine were also effective when given as late as 6 h after CCl4. The protective effects of these amino acids, however, were no longer evident when observations of CCl4-induced necrosis were made at 72 h, except for cystine, which retained its protective potential. Protective amino acid administration did not modify the concentration of CCl4 in liver, nor did it decrease the intensity of the covalent binding of CCl4 reactive metabolites to cellular constituents or the CCl4-induced lipid peroxidation. Consequently, protection cannot be attributed to modulation of these parameters. Cystine, tyrosine and aspartic acid significantly lowered body temperature of the CCl4-treated rats, while methionine did not. Combined, these results suggest that the protective effect is not attributable to lowering of body temperature in CCl4-treated animals. Protection probably results from changes in the cell response to injury promoted by amino acid administration." @default.
- W2261562213 created "2016-06-24" @default.
- W2261562213 creator A5012561202 @default.
- W2261562213 creator A5018717444 @default.
- W2261562213 creator A5037896599 @default.
- W2261562213 creator A5065834691 @default.
- W2261562213 date "1983-04-01" @default.
- W2261562213 modified "2023-09-23" @default.
- W2261562213 title "Prevention of carbon tetrachloride-induced liver necrosis by several amino acids." @default.
- W2261562213 cites W1971588896 @default.
- W2261562213 cites W1973483019 @default.
- W2261562213 cites W1994156563 @default.
- W2261562213 cites W2000005434 @default.
- W2261562213 cites W2014375497 @default.
- W2261562213 cites W2045231599 @default.
- W2261562213 cites W2057307245 @default.
- W2261562213 cites W2079097043 @default.
- W2261562213 cites W2171473267 @default.
- W2261562213 cites W2255996618 @default.
- W2261562213 cites W2272893328 @default.
- W2261562213 cites W2402319693 @default.
- W2261562213 cites W2415349648 @default.
- W2261562213 cites W2469585987 @default.
- W2261562213 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2040682" @default.
- W2261562213 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6849812" @default.
- W2261562213 hasPublicationYear "1983" @default.
- W2261562213 type Work @default.
- W2261562213 sameAs 2261562213 @default.
- W2261562213 citedByCount "6" @default.
- W2261562213 countsByYear W22615622132013 @default.
- W2261562213 crossrefType "journal-article" @default.
- W2261562213 hasAuthorship W2261562213A5012561202 @default.
- W2261562213 hasAuthorship W2261562213A5018717444 @default.
- W2261562213 hasAuthorship W2261562213A5037896599 @default.
- W2261562213 hasAuthorship W2261562213A5065834691 @default.
- W2261562213 hasConcept C102124568 @default.
- W2261562213 hasConcept C149971331 @default.
- W2261562213 hasConcept C178790620 @default.
- W2261562213 hasConcept C181199279 @default.
- W2261562213 hasConcept C185592680 @default.
- W2261562213 hasConcept C2776165026 @default.
- W2261562213 hasConcept C2777359374 @default.
- W2261562213 hasConcept C2777608289 @default.
- W2261562213 hasConcept C2779201268 @default.
- W2261562213 hasConcept C2780912031 @default.
- W2261562213 hasConcept C2781208047 @default.
- W2261562213 hasConcept C29730261 @default.
- W2261562213 hasConcept C515207424 @default.
- W2261562213 hasConcept C538909803 @default.
- W2261562213 hasConcept C55493867 @default.
- W2261562213 hasConcept C86803240 @default.
- W2261562213 hasConcept C98274493 @default.
- W2261562213 hasConceptScore W2261562213C102124568 @default.
- W2261562213 hasConceptScore W2261562213C149971331 @default.
- W2261562213 hasConceptScore W2261562213C178790620 @default.
- W2261562213 hasConceptScore W2261562213C181199279 @default.
- W2261562213 hasConceptScore W2261562213C185592680 @default.
- W2261562213 hasConceptScore W2261562213C2776165026 @default.
- W2261562213 hasConceptScore W2261562213C2777359374 @default.
- W2261562213 hasConceptScore W2261562213C2777608289 @default.
- W2261562213 hasConceptScore W2261562213C2779201268 @default.
- W2261562213 hasConceptScore W2261562213C2780912031 @default.
- W2261562213 hasConceptScore W2261562213C2781208047 @default.
- W2261562213 hasConceptScore W2261562213C29730261 @default.
- W2261562213 hasConceptScore W2261562213C515207424 @default.
- W2261562213 hasConceptScore W2261562213C538909803 @default.
- W2261562213 hasConceptScore W2261562213C55493867 @default.
- W2261562213 hasConceptScore W2261562213C86803240 @default.
- W2261562213 hasConceptScore W2261562213C98274493 @default.
- W2261562213 hasIssue "2" @default.
- W2261562213 hasLocation W22615622131 @default.
- W2261562213 hasOpenAccess W2261562213 @default.
- W2261562213 hasPrimaryLocation W22615622131 @default.
- W2261562213 hasRelatedWork W141642723 @default.
- W2261562213 hasRelatedWork W1971397936 @default.
- W2261562213 hasRelatedWork W1981805973 @default.
- W2261562213 hasRelatedWork W1993027755 @default.
- W2261562213 hasRelatedWork W2001093766 @default.
- W2261562213 hasRelatedWork W2077029966 @default.
- W2261562213 hasRelatedWork W2085864923 @default.
- W2261562213 hasRelatedWork W2261562213 @default.
- W2261562213 hasRelatedWork W2802766963 @default.
- W2261562213 hasRelatedWork W76384867 @default.
- W2261562213 hasVolume "64" @default.
- W2261562213 isParatext "false" @default.
- W2261562213 isRetracted "false" @default.
- W2261562213 magId "2261562213" @default.
- W2261562213 workType "article" @default.