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• W2261823250 endingPage "2372" @default.
• W2261823250 startingPage "2365" @default.
• W2261823250 abstract "Dual-energy X-ray absorptiometry (DXA) percent (%) fat estimates may be inaccurate in young children, who typically have high tissue hydration levels. This study was designed to provide a comprehensive analysis of pediatric tissue hydration effects on DXA %fat estimates. Phase 1 was experimental and included three in vitro studies to establish the physical basis of DXA %fat-estimation models. Phase 2 extended phase 1 models and consisted of theoretical calculations to estimate the %fat errors emanating from previously reported pediatric hydration effects. Phase 1 experiments supported the two-compartment DXA soft tissue model and established that pixel ratio of low to high energy (R values) are a predictable function of tissue elemental content. In phase 2, modeling of reference body composition values from birth to age 120 mo revealed that %fat errors will arise if a constant adult lean soft tissue R value is applied to the pediatric population; the maximum %fat error, approximately 0.8%, would be present at birth. High tissue hydration, as observed in infants and young children, leads to errors in DXA %fat estimates. The magnitude of these errors based on theoretical calculations is small and may not be of clinical or research significance." @default.
• W2261823250 created "2016-06-24" @default.
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• W2261823250 date "2000-12-01" @default.
• W2261823250 modified "2023-10-10" @default.
• W2261823250 title "Dual-energy X-ray absorptiometry: analysis of pediatric fat estimate errors due to tissue hydration effects" @default.
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• W2261823250 doi "https://doi.org/10.1152/jappl.2000.89.6.2365" @default.
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