Matches in SemOpenAlex for { <https://semopenalex.org/work/W2262117041> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2262117041 abstract "Author(s): Sorber, Katherine | Advisor(s): DeRisi, Joseph L | Abstract: This graduate work consists of projects concerned with functions of RNA, use of high throughput sequencing technology, and the molecular biology of the malaria parasite Plasmodium falciparum. The intricacies of recognition of mRNA molecules by yeast transport machinery were explored in an unbiased manner, leading to identification of both primary sequence and secondary structural motifs. High throughput sequencing was used to recover a new type of bornavirus associated with proventricular dilatation disease in psittacine birds. High throughput sequencing was again used to find leads as to the genetic determinant of artemisinin resistance in Plasmodium falciparum, finding an amplification on chromosome 10 as the most promising lead. Parasite response to artemisinin was also studied at the transcriptional level using microarrays to document the entry into and recovery from the ring-like dormant state induced in Plasmodium falciparum by artemisinin. Finally, splicing in Plasmodium falciparum was investigated by sequencing mRNA from four timepoints in the blood stages of the parasite. Specific software was written to extract all exon-exon junctions within that dataset and higher order analysis revealed previously unknown splice sites, hundreds of alternative splicing events, and the presence of spliced antisense RNAs in the transcriptome." @default.
- W2262117041 created "2016-06-24" @default.
- W2262117041 creator A5070533404 @default.
- W2262117041 date "2010-01-01" @default.
- W2262117041 modified "2023-09-23" @default.
- W2262117041 title "Nucleic acid methods in yeast and infectious disease" @default.
- W2262117041 hasPublicationYear "2010" @default.
- W2262117041 type Work @default.
- W2262117041 sameAs 2262117041 @default.
- W2262117041 citedByCount "0" @default.
- W2262117041 crossrefType "journal-article" @default.
- W2262117041 hasAuthorship W2262117041A5070533404 @default.
- W2262117041 hasConcept C104317684 @default.
- W2262117041 hasConcept C132917006 @default.
- W2262117041 hasConcept C141231307 @default.
- W2262117041 hasConcept C150194340 @default.
- W2262117041 hasConcept C162317418 @default.
- W2262117041 hasConcept C194583182 @default.
- W2262117041 hasConcept C203014093 @default.
- W2262117041 hasConcept C2776120307 @default.
- W2262117041 hasConcept C2778048844 @default.
- W2262117041 hasConcept C2778371730 @default.
- W2262117041 hasConcept C36823959 @default.
- W2262117041 hasConcept C51679486 @default.
- W2262117041 hasConcept C54355233 @default.
- W2262117041 hasConcept C54458228 @default.
- W2262117041 hasConcept C67705224 @default.
- W2262117041 hasConcept C70721500 @default.
- W2262117041 hasConcept C86803240 @default.
- W2262117041 hasConcept C95371953 @default.
- W2262117041 hasConceptScore W2262117041C104317684 @default.
- W2262117041 hasConceptScore W2262117041C132917006 @default.
- W2262117041 hasConceptScore W2262117041C141231307 @default.
- W2262117041 hasConceptScore W2262117041C150194340 @default.
- W2262117041 hasConceptScore W2262117041C162317418 @default.
- W2262117041 hasConceptScore W2262117041C194583182 @default.
- W2262117041 hasConceptScore W2262117041C203014093 @default.
- W2262117041 hasConceptScore W2262117041C2776120307 @default.
- W2262117041 hasConceptScore W2262117041C2778048844 @default.
- W2262117041 hasConceptScore W2262117041C2778371730 @default.
- W2262117041 hasConceptScore W2262117041C36823959 @default.
- W2262117041 hasConceptScore W2262117041C51679486 @default.
- W2262117041 hasConceptScore W2262117041C54355233 @default.
- W2262117041 hasConceptScore W2262117041C54458228 @default.
- W2262117041 hasConceptScore W2262117041C67705224 @default.
- W2262117041 hasConceptScore W2262117041C70721500 @default.
- W2262117041 hasConceptScore W2262117041C86803240 @default.
- W2262117041 hasConceptScore W2262117041C95371953 @default.
- W2262117041 hasLocation W22621170411 @default.
- W2262117041 hasOpenAccess W2262117041 @default.
- W2262117041 hasPrimaryLocation W22621170411 @default.
- W2262117041 hasRelatedWork W1964408180 @default.
- W2262117041 hasRelatedWork W1981252367 @default.
- W2262117041 hasRelatedWork W1997850371 @default.
- W2262117041 hasRelatedWork W2002900693 @default.
- W2262117041 hasRelatedWork W2020641501 @default.
- W2262117041 hasRelatedWork W2077163521 @default.
- W2262117041 hasRelatedWork W2079721682 @default.
- W2262117041 hasRelatedWork W2102155970 @default.
- W2262117041 hasRelatedWork W2110952939 @default.
- W2262117041 hasRelatedWork W2113038420 @default.
- W2262117041 hasRelatedWork W2114238087 @default.
- W2262117041 hasRelatedWork W2152456724 @default.
- W2262117041 hasRelatedWork W2155705270 @default.
- W2262117041 hasRelatedWork W2274064007 @default.
- W2262117041 hasRelatedWork W2401515637 @default.
- W2262117041 hasRelatedWork W2406664911 @default.
- W2262117041 hasRelatedWork W2614266406 @default.
- W2262117041 hasRelatedWork W2787452337 @default.
- W2262117041 hasRelatedWork W2904876692 @default.
- W2262117041 hasRelatedWork W2941618024 @default.
- W2262117041 isParatext "false" @default.
- W2262117041 isRetracted "false" @default.
- W2262117041 magId "2262117041" @default.
- W2262117041 workType "article" @default.