Matches in SemOpenAlex for { <https://semopenalex.org/work/W2263116563> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2263116563 abstract "ABSTRACT Aim: Psychological distress and chemotherapy-related side effects frequently co-occur in patients with lung cancer (LC). Clinical experience suggests that LC is associated with psychological distress that may contribute to worse chemotherapy-related side effects. Using questionnaires, we tried to describe clinical characteristics of psychological distress and chemotherapy-related side effects, and to examine the influence of psychological distress on side effects among LC patients during chemotherapy. Methods: Patients with LC receiving chemotherapy completed an assessment that captured clinical characteristics, psychological state (anxiety, depression and insomnia) and treatment-related side effects (nausea, vomiting, constipation and fatigue). Psychological distress was assessed by Hospital Anxiety and Depression Scale and by Pittsburgh Sleep Quality Index (PSQI). Nausea, vomiting and constipation were examined as defined by the National Cancer Institute Common Terminology Criteria for Adverse Events, while fatigue was scored on a 10-point scale ranging from 0 =“not present” to 10 = “as bad as you can imagine”. Results: In total, 93 patients with a mean age of 58 years joined this study. Grade 0 to 3 toxicity occurred in 100% of the patients. Patients with LC who were younger than 58 years, female, retired from work, and had less medical insurance were significantly likely to experience more severe vomiting (p = 0.018), constipation (p = 0.004), fatigue (p = 0.004) and nausea (p = 0.047). On the other side, patients with LC who were female, had poor living conditions, and retired from work were significantly likely to experience more severe insomnia (p = 0.014), anxiety and depression (p = 0.030 and p = 0.004 respectively) and insomnia (p = 0.002). Those with more severe depression complaints had significantly more vomiting (p = 0.035), while those with more severe anxiety and insomnia complaints had significantly more fatigue (p = 0.038 and p = 0.000 respectively). Conclusions: Psychological distress is a prevalent problem in LC and it was associated with an increased treatment-related side effect during chemotherapy. Improving psychological health can be a possible solution to decrease chemotherapy-related side effects so that may reduce treatment interruptions, improve the cure rate and increase quality of life following treatment. Disclosure: All authors have declared no conflicts of interest." @default.
- W2263116563 created "2016-06-24" @default.
- W2263116563 creator A5006103766 @default.
- W2263116563 creator A5060978443 @default.
- W2263116563 creator A5061624898 @default.
- W2263116563 creator A5083862030 @default.
- W2263116563 date "2014-09-01" @default.
- W2263116563 modified "2023-09-29" @default.
- W2263116563 title "Clinical Characteristics and Psychological Associations of Cancer Chemotherapy–Related Side Effects in Patients with Lung Cancer" @default.
- W2263116563 doi "https://doi.org/10.1093/annonc/mdu352.15" @default.
- W2263116563 hasPublicationYear "2014" @default.
- W2263116563 type Work @default.
- W2263116563 sameAs 2263116563 @default.
- W2263116563 citedByCount "0" @default.
- W2263116563 crossrefType "journal-article" @default.
- W2263116563 hasAuthorship W2263116563A5006103766 @default.
- W2263116563 hasAuthorship W2263116563A5060978443 @default.
- W2263116563 hasAuthorship W2263116563A5061624898 @default.
- W2263116563 hasAuthorship W2263116563A5083862030 @default.
- W2263116563 hasBestOaLocation W22631165631 @default.
- W2263116563 hasConcept C118552586 @default.
- W2263116563 hasConcept C126322002 @default.
- W2263116563 hasConcept C139719470 @default.
- W2263116563 hasConcept C162324750 @default.
- W2263116563 hasConcept C197934379 @default.
- W2263116563 hasConcept C2776256026 @default.
- W2263116563 hasConcept C2776694085 @default.
- W2263116563 hasConcept C2776867660 @default.
- W2263116563 hasConcept C2777793932 @default.
- W2263116563 hasConcept C2780580376 @default.
- W2263116563 hasConcept C2780852908 @default.
- W2263116563 hasConcept C2781112942 @default.
- W2263116563 hasConcept C2781210498 @default.
- W2263116563 hasConcept C558461103 @default.
- W2263116563 hasConcept C71924100 @default.
- W2263116563 hasConceptScore W2263116563C118552586 @default.
- W2263116563 hasConceptScore W2263116563C126322002 @default.
- W2263116563 hasConceptScore W2263116563C139719470 @default.
- W2263116563 hasConceptScore W2263116563C162324750 @default.
- W2263116563 hasConceptScore W2263116563C197934379 @default.
- W2263116563 hasConceptScore W2263116563C2776256026 @default.
- W2263116563 hasConceptScore W2263116563C2776694085 @default.
- W2263116563 hasConceptScore W2263116563C2776867660 @default.
- W2263116563 hasConceptScore W2263116563C2777793932 @default.
- W2263116563 hasConceptScore W2263116563C2780580376 @default.
- W2263116563 hasConceptScore W2263116563C2780852908 @default.
- W2263116563 hasConceptScore W2263116563C2781112942 @default.
- W2263116563 hasConceptScore W2263116563C2781210498 @default.
- W2263116563 hasConceptScore W2263116563C558461103 @default.
- W2263116563 hasConceptScore W2263116563C71924100 @default.
- W2263116563 hasLocation W22631165631 @default.
- W2263116563 hasOpenAccess W2263116563 @default.
- W2263116563 hasPrimaryLocation W22631165631 @default.
- W2263116563 hasRelatedWork W1486726835 @default.
- W2263116563 hasRelatedWork W1568972147 @default.
- W2263116563 hasRelatedWork W1976510183 @default.
- W2263116563 hasRelatedWork W2076393655 @default.
- W2263116563 hasRelatedWork W2148321021 @default.
- W2263116563 hasRelatedWork W2391438002 @default.
- W2263116563 hasRelatedWork W2472104251 @default.
- W2263116563 hasRelatedWork W2489221928 @default.
- W2263116563 hasRelatedWork W2889765329 @default.
- W2263116563 hasRelatedWork W2912507785 @default.
- W2263116563 hasRelatedWork W2944384981 @default.
- W2263116563 hasRelatedWork W2963925259 @default.
- W2263116563 hasRelatedWork W3024666072 @default.
- W2263116563 hasRelatedWork W3031596225 @default.
- W2263116563 hasRelatedWork W3032478540 @default.
- W2263116563 hasRelatedWork W3080457208 @default.
- W2263116563 hasRelatedWork W3104104172 @default.
- W2263116563 hasRelatedWork W3212308223 @default.
- W2263116563 hasRelatedWork W3214714405 @default.
- W2263116563 hasRelatedWork W3082905490 @default.
- W2263116563 isParatext "false" @default.
- W2263116563 isRetracted "false" @default.
- W2263116563 magId "2263116563" @default.
- W2263116563 workType "article" @default.