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• W2263148370 abstract "Abstract A potentially vital pathway in the processing of spatial memory is the pathway from ventral hippocampus to medial prefrontal cortex (vHPC–mPFC). To assess long‐term potentiation ( LTP ) induction and maintenance across days in this pathway, the effects of several induction paradigms were compared in awake, freely moving rats. Two different high‐frequency stimulation ( HFS ) protocols generated LTP lasting no longer than 1 week. However, after delivering HFS on three consecutive days, LTP lasted an average of 20 days, due mainly to the greater initial induction. Thus the pathway does not require extensive multi‐day stimulation to induce LTP , as for other intra‐neocortical pathways, but also it does not exhibit the extremely long‐lasting and stable LTP previously observed in area CA 1 and the dentate gyrus. By using bilaterally placed stimulating and recording electrodes, we found that HFS in one vHPC generated responses and LTP in the contralateral mPFC, even when the ipsilateral mPFC was inactivated by CNQX . We attribute this crossed response to a polysynaptic pathway from the vHPC to the contralateral mPFC. Finally, we found that repeated overnight exposure to an enriched environment also potentiated the vHPC–mPFC response, but this too was a transient effect lasting < 9 days, declining to baseline even before the enriched environment treatment was completed. Overall, these findings are consistent with the view that potentiation of vHPC–mPFC pathway may play a key role in promoting the hippocampus–mPFC interplay that, over days, leads to long‐term storage in the frontal cortex of memories that are independent of the hippocampus." @default.
• W2263148370 created "2016-06-24" @default.
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• W2263148370 date "2016-02-10" @default.
• W2263148370 modified "2023-10-18" @default.
• W2263148370 title "The persistence of long-term potentiation in the projection from ventral hippocampus to medial prefrontal cortex in awake rats" @default.
• W2263148370 cites W1688233106 @default.
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• W2263148370 cites W1939596644 @default.
• W2263148370 cites W1964264008 @default.
• W2263148370 cites W1965545113 @default.
• W2263148370 cites W1967531155 @default.
• W2263148370 cites W1968961777 @default.
• W2263148370 cites W1969735301 @default.
• W2263148370 cites W1971893902 @default.
• W2263148370 cites W1985582399 @default.
• W2263148370 cites W1986203780 @default.
• W2263148370 cites W1987895660 @default.
• W2263148370 cites W1987984193 @default.
• W2263148370 cites W1989162757 @default.
• W2263148370 cites W1990186908 @default.
• W2263148370 cites W1992084781 @default.
• W2263148370 cites W1999143269 @default.
• W2263148370 cites W2000301136 @default.
• W2263148370 cites W2004377368 @default.
• W2263148370 cites W2005173683 @default.
• W2263148370 cites W2008231906 @default.
• W2263148370 cites W2011844804 @default.
• W2263148370 cites W2017816448 @default.
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• W2263148370 cites W2020896566 @default.
• W2263148370 cites W2024758252 @default.
• W2263148370 cites W2027320657 @default.
• W2263148370 cites W2029465497 @default.
• W2263148370 cites W2046183844 @default.
• W2263148370 cites W2046350676 @default.
• W2263148370 cites W2047057213 @default.
• W2263148370 cites W2050106447 @default.
• W2263148370 cites W2050841371 @default.
• W2263148370 cites W2054821149 @default.
• W2263148370 cites W2057597062 @default.
• W2263148370 cites W2058223585 @default.
• W2263148370 cites W2059462064 @default.
• W2263148370 cites W2063896962 @default.
• W2263148370 cites W2065738753 @default.
• W2263148370 cites W2070614165 @default.
• W2263148370 cites W2072060777 @default.
• W2263148370 cites W2072760880 @default.
• W2263148370 cites W2077664665 @default.
• W2263148370 cites W2079311820 @default.
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• W2263148370 cites W2090413950 @default.
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• W2263148370 cites W2093072166 @default.
• W2263148370 cites W2098570344 @default.
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• W2263148370 doi "https://doi.org/10.1111/ejn.13167" @default.
• W2263148370 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26750170" @default.
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