Matches in SemOpenAlex for { <https://semopenalex.org/work/W2263396562> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2263396562 endingPage "432" @default.
- W2263396562 startingPage "427" @default.
- W2263396562 abstract "Objective To explore the pathophysiological changes behind somatosensory evoked po-tential (SEP) defect and its diagnostic value in an established model of spinal cord chronic compression. Methods Total 15 rats were operated with implantation of a water-absorbing polymer sheet in cervical spinal canal, which expanded gradually to induce chronic compression to the spinal cord. At 6 months after surgery, SEP, radioiogical and pathohistological/istochemistry evaluations were done. Results Spinal cord in 15 rats showed significant morphological compressed deformity after chronic compression. It was also characterized by higher contrast intensity and distortion of gray matter and whiter matter under micro-CT e-valuations. SEP revealed that nine rats had prolonged latency and/or decreased amplitude. Based on their different SEP response, they were categorized into: type Ⅰ (n=6), type Ⅱa (n=5), type Ⅱb (n=2), type Ⅲ (n=2), and type Ⅳ (n=0). Compression ratio was not different between normal and abnormal SEP responses in the rats. Compared with the rats with normal SEP responses, the spinal cord of rats with normal SEP responses showed less myelin staining in white matter(Ⅱa: 106±12 vs.Ⅰ: 121±8; P=0.038), less contrast medium density in posterior dorsal column (Ⅱa: 95±5 vs. Ⅰ: 87±6; P=0.042), lower neuron density and cavitation in gray mat-ter[Ⅱa: (25±8)/mm~2 vs. Ⅰ: (29±6)/mm~2, P>0.05]. Less myelin staining in posterior column whiter matter could be seen in type Ⅱb and Ⅲ. Neuron density in posterior horn of gray matter were (16±5)/mm~2 and (14± 5)/mm~2 respectively. Histological cystic cavitations and sinusoidal dilation of veins were noted in spinal cord with significant distortion after compression. Conclusion SEP responses reflected the severity of spinal cord posterior tract and horn damage in chronic compressive injuries after gross appearance changes.Key words: Spinal cord compression; Disease models,animal; Evoked potentials,somatosensory" @default.
- W2263396562 created "2016-06-24" @default.
- W2263396562 creator A5016752301 @default.
- W2263396562 creator A5036451023 @default.
- W2263396562 creator A5042083053 @default.
- W2263396562 date "2010-04-01" @default.
- W2263396562 modified "2023-09-28" @default.
- W2263396562 title "The establishment of the experimental chronic compressive myelopathy and the mechanism of somatosensory-evoked potential's evaluation" @default.
- W2263396562 doi "https://doi.org/10.3760/cma.j.issn.0253-2352.2010.04.021" @default.
- W2263396562 hasPublicationYear "2010" @default.
- W2263396562 type Work @default.
- W2263396562 sameAs 2263396562 @default.
- W2263396562 citedByCount "0" @default.
- W2263396562 crossrefType "journal-article" @default.
- W2263396562 hasAuthorship W2263396562A5016752301 @default.
- W2263396562 hasAuthorship W2263396562A5036451023 @default.
- W2263396562 hasAuthorship W2263396562A5042083053 @default.
- W2263396562 hasConcept C105702510 @default.
- W2263396562 hasConcept C118552586 @default.
- W2263396562 hasConcept C126322002 @default.
- W2263396562 hasConcept C126838900 @default.
- W2263396562 hasConcept C142724271 @default.
- W2263396562 hasConcept C143409427 @default.
- W2263396562 hasConcept C161941745 @default.
- W2263396562 hasConcept C2778231337 @default.
- W2263396562 hasConcept C2778609137 @default.
- W2263396562 hasConcept C2780775167 @default.
- W2263396562 hasConcept C2781192897 @default.
- W2263396562 hasConcept C2989005 @default.
- W2263396562 hasConcept C42219234 @default.
- W2263396562 hasConcept C529278444 @default.
- W2263396562 hasConcept C71924100 @default.
- W2263396562 hasConceptScore W2263396562C105702510 @default.
- W2263396562 hasConceptScore W2263396562C118552586 @default.
- W2263396562 hasConceptScore W2263396562C126322002 @default.
- W2263396562 hasConceptScore W2263396562C126838900 @default.
- W2263396562 hasConceptScore W2263396562C142724271 @default.
- W2263396562 hasConceptScore W2263396562C143409427 @default.
- W2263396562 hasConceptScore W2263396562C161941745 @default.
- W2263396562 hasConceptScore W2263396562C2778231337 @default.
- W2263396562 hasConceptScore W2263396562C2778609137 @default.
- W2263396562 hasConceptScore W2263396562C2780775167 @default.
- W2263396562 hasConceptScore W2263396562C2781192897 @default.
- W2263396562 hasConceptScore W2263396562C2989005 @default.
- W2263396562 hasConceptScore W2263396562C42219234 @default.
- W2263396562 hasConceptScore W2263396562C529278444 @default.
- W2263396562 hasConceptScore W2263396562C71924100 @default.
- W2263396562 hasIssue "4" @default.
- W2263396562 hasLocation W22633965621 @default.
- W2263396562 hasOpenAccess W2263396562 @default.
- W2263396562 hasPrimaryLocation W22633965621 @default.
- W2263396562 hasRelatedWork W1980282965 @default.
- W2263396562 hasRelatedWork W1990066190 @default.
- W2263396562 hasRelatedWork W1992430359 @default.
- W2263396562 hasRelatedWork W1993221966 @default.
- W2263396562 hasRelatedWork W2003228301 @default.
- W2263396562 hasRelatedWork W2038999647 @default.
- W2263396562 hasRelatedWork W2062253939 @default.
- W2263396562 hasRelatedWork W2064157330 @default.
- W2263396562 hasRelatedWork W2076065238 @default.
- W2263396562 hasRelatedWork W2144103603 @default.
- W2263396562 hasRelatedWork W2167980768 @default.
- W2263396562 hasRelatedWork W2344217021 @default.
- W2263396562 hasRelatedWork W2372146965 @default.
- W2263396562 hasRelatedWork W2378267094 @default.
- W2263396562 hasRelatedWork W2415046684 @default.
- W2263396562 hasRelatedWork W2435825471 @default.
- W2263396562 hasRelatedWork W3032307600 @default.
- W2263396562 hasRelatedWork W3146705427 @default.
- W2263396562 hasRelatedWork W2184134867 @default.
- W2263396562 hasRelatedWork W2415692653 @default.
- W2263396562 hasVolume "30" @default.
- W2263396562 isParatext "false" @default.
- W2263396562 isRetracted "false" @default.
- W2263396562 magId "2263396562" @default.
- W2263396562 workType "article" @default.