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- W2263931843 abstract "<p><strong>Abstract</strong></p><p><strong>Background: </strong>Tuberculous pleurisy is a common extrapulmonary manifestation and is second to tuberculous lymphadenitis. Due to its paucibacillary in origin, its diagnosis is a challenge. Furthermore, it is also complicated by the emergence of MDR. Gene Xpert MTB/RIF is a new rapid promising innovation for the detection of mycobacterium tuberculosis and its resistance to Rifampicin, giving result within two hours.</p><p><strong>Objective: </strong>To evaluate the diagnostic role of Gene Xpert MTB/RIF in suspected cases of tuberculous pleurisy.</p><p><strong>Study Design: </strong>Cross sectional study.</p><p><strong>Study Setting: </strong>Institute of Chest Medicine Mayo Hospital – a Tertiary Care Hospital affiliated with King Edward Medical University, Lahore.</p><p><strong>Methodology: </strong>The study group, one hundred (M-60 and F-40) cases having exudative, predominantly lymphocytic pleural effusion with strong suspicion of tuberculous in origin were enrolled randomly for Gene Xpert MTB / RIF.</p><p><strong>Results: </strong>Among one hundred study cases, Gene Xpert detected mycobacterium tuberculosis in 12(12%) cases [M-8 (13.3%) and F-4 (10%)]. Resistance to Rifampacin was detected in 6 (6%) cases [M-2 (3.3%) and F-4 (10%)].</p><p><strong>Conclusion: </strong>Gene Xpert MTB/RIF is a useful new rapid promising technique to diagnose tuberculous pleurisy. Although at present it has limited availability and utility.</p><p><strong>Key Words: </strong>Gene Xpert. MTB – Mycobacterium tuberculosis. RIF – Rifampacin. TB – Tuberculosis. MDR – Multidrug resistance.</p>" @default.
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- W2263931843 date "2016-02-13" @default.
- W2263931843 modified "2023-09-23" @default.
- W2263931843 title "Gene Xpert MTB / RIF – Diagnostic Role in Tuberculous Pleurisy" @default.
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- W2263931843 doi "https://doi.org/10.21649/akemu.v22i1.803" @default.
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