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- W2263989655 abstract "Objective To explore the relationship between the changes of urinary β2-microglobin (β2-MG), N-acetyl-beta-D-glucosaminidase (NAG) and kidney injury molecule-1 (KIM-1) in patients with contrast agent-induced nephropathy (CIN) by analyzing the level of urinary β2-MG, NAG and KIM-1. Method 49 cases of CIN patients and 52 cases of healthy volunteers were enrolled into the study. The levels of urinary β2-MG, NAG and KIM-1 were determined by ELISA. Result The level of β2-MG (594.62±87.93)mg / L, NAG (24.52±4.64)U / L and KIM-1 (4.68± .83)ng / mL in CIN patients was significant higher than the healthy subjects [β2-MG (108.16± 10.55)mg / L,NAG (8.74 ±1.75)U / L,KIM-1 (0.28 ±0.10)ng / mL]. And the level of creatine of CIN patients (25.09±7.50)ml / min was significant lower than the healthy control subjects (83.75±33.84) ml / min. Conclusion The level of urinary β2-MG, NAG and KIM-1 is elevated in CIN patients, indicating the impairment of tubular function. β2-MG, NAG and KIM-1 may be useful indicators for the monitoring of kidney function in CIN patients." @default.
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- W2263989655 date "2009-01-01" @default.
- W2263989655 modified "2023-09-28" @default.
- W2263989655 title "The changes of urinary β2-microglobin, N-acetyl-beta-D-glucosaminidase and kidney injury molecule-1 in patients with contrast agent-induced nephropathy." @default.
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