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- W2264830064 abstract "textabstractAlthough drug therapy often results in beneficial effects and improves functionalstatus, adverse consequences of pharmacotherapy are a major patient safetyconcern, especially in the growing older population '.In the well-known report'To err is human: building a safer health care system'', it was brought forward thata substantial number of patients is harmed by adverse drug events in medical care.This report placed patient safety and drug safety on the international agenda andwas the basis for many policy and health care initiatives to make health care safer.Apart from the vulnerability of a patient to develop an adverse drug reaction,drug safety has several aspects, among which are deficient product quality, qualityof prescribing and administration, and patient compliance. In this thesis, we focuson the quality of prescribing and on adverse consequences of pharmacotherapyin the elderly, because in the aging western countries this is a vulnerable patientgroup of increasing importance. In view of multiple co-morbidity, changes inpharmacokinetics and pharmacodynamics and concomitant use of several drugssimultaneously (polypharmacy), elderly people are at increased risk of drug-relatedproblems. Moreover, several studies on drug utilisation and quality of prescribingin elderly patients have demonstrated high levels of drug use and a considerablenumber of patients receiving inappropriate medications. lnappropriatemedication use for older adults can be defined as medication use for which thepotential harm outweighs the potential benefit and for which a good alternativeis available.This alternative could be the prescribing of an other (safer) drug orprescribing a drug in a lower (geriatric) dose, in order to decrease the risk of adversedrug events in this vulnerable group." @default.
- W2264830064 created "2016-06-24" @default.
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- W2264830064 date "2006-02-15" @default.
- W2264830064 modified "2023-09-23" @default.
- W2264830064 title "Adverse Consequences of Drug Use in the Elderly" @default.
- W2264830064 hasPublicationYear "2006" @default.
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