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• W2265164857 abstract "The critical importance of algorithms for orienting proteins in the lipid bilayer stems from the extreme difficulty in obtaining experimental data about the membrane boundaries. Here, we present a computational method for positioning protein structures in the membrane, based on the sole alpha carbon coordinates and, therefore, compatible with both high and low structural resolutions. Our algorithm follows a new and simple approach, by treating the membrane assignment problem as a binary classification. Compared with the state-of-the-art algorithms, our method achieves similar accuracy, while being faster. Finally, our open-source software is also capable of processing coarse-grained models of protein structures." @default.
• W2265164857 created "2016-06-24" @default.
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• W2265164857 date "2015-12-19" @default.
• W2265164857 modified "2023-10-01" @default.
• W2265164857 title "Membrane positioning for high- and low-resolution protein structures through a binary classification approach" @default.
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• W2265164857 doi "https://doi.org/10.1093/protein/gzv063" @default.
• W2265164857 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26685702" @default.
• W2265164857 hasPublicationYear "2015" @default.
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