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- W2265361804 abstract "Nasopharyngeal cancer (NPC) is prevalent in Taiwan. Radiotherapy is the main treatment modality but its complications and sequelae have great impact on patients. This study assessed their quality of life (QoL) and investigated the influencing factors to their QoL.A total of 43 NPC patients, who were postradiotherapy and recurrence-free, self-assessed their quality of life by the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30 v.3) and the EORTC Head and Neck Cancer Module (EORTC QLQ H&N35).The results showed that the mean age was 52.0±8.7 years, 39.5% was male, the mean duration after radiotherapy was 114.4±94.4 months. The emotional functioning(69.0±28.0) and cognitive functioning (70.5±26.2) were much affected. Fatigue, insomnia and pain were their major concerns. The mean total score of global QoL was 52.7±24.2.The most suffering symptoms specific for NPC were dry month (72.1±29.9), sticky saliva (59.7±36.8) and teeth problem(48.1±32.8). Multiple linear regression analysis revealed that role functioning of QLQC30 (explained 46.2% of variance) and insomnia (explained 12.4% of variance) were the significant predictors of global QoL.In conclusion, our results demonstrate that the NPC patients after radiotherapy had negative emotion, distressful physical symptoms and poorer quality of life. The role functioning and physical distress symptoms played important role in the perception of QoL. Biopsychosocial medical care is essential for improving the QoL. The measurement of EORTC QLQ-C30 could be a useful instrument to early detect patients' physical and psychological concerns." @default.
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- W2265361804 date "2005-04-01" @default.
- W2265361804 modified "2023-09-23" @default.
- W2265361804 title "Quality of Life in Patients with Nasopharyngeal Cancer after Radiotherapy" @default.
- W2265361804 doi "https://doi.org/10.29475/tfmr.200504.0004" @default.
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