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- W2265670537 abstract "The Gal4-UAS combinatorial genetic system is a versatile tool to study gene function as it offers spatial and temporal control over transgene expression. We adapted the Gal4-UAS system for its application in zebrafish, generated transgenic tissue-specific Gal4 strains, a Gal4 effector strain (Kaloop) for gene-expression mapping and a Gal4 based subcellular labelling system to study the dynamics of cell components. Applying these systems, we could show that the secondary octaval nucleus is likely derived from rhombomere 5 of the embryonic zebrafish hindbrain. Furthermore, we observed that in contrast to the classic model based on cell culture observations, the proximity of the centrosome does not determine the site of axon outgrowth in tegmental hindbrain nuclei neurons in vivo." @default.
- W2265670537 created "2016-06-24" @default.
- W2265670537 creator A5021115704 @default.
- W2265670537 date "2010-01-01" @default.
- W2265670537 modified "2023-09-24" @default.
- W2265670537 title "Establishment of combinatorial genetics in zebrafish for analyzing cellular mechanisms of hindbrain development" @default.
- W2265670537 hasPublicationYear "2010" @default.
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