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- W2265744462 abstract "Many of the most common human cancers disseminate from the site of primary tumour growth to distant tissues via the vessels and organs of the lymphatic system. In melanomas, cancers of the breast and colorectum, and in head and neck squamous cell carcinomas, early metastasis to lymph nodes is a common clinical finding, and one that is associated with poorer prognosis.Treatments to specifically block dissemination through the lymphatic network could in theory provide an independent therapy for some cancers, or at least an adjunct to existing chemotherapy. However, such a rational basis for the design of treatments is currently hindered by our poor understanding of the fundamental biology of lymphatics, and in particular lymphatic endothelial cell (LEC) biology." @default.
- W2265744462 created "2016-06-24" @default.
- W2265744462 creator A5030823404 @default.
- W2265744462 date "2007-01-01" @default.
- W2265744462 modified "2023-10-03" @default.
- W2265744462 title "Lymphatic Markers, Tumour Lymphangiogenesis and Lymph Node Metastasis" @default.
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- W2265744462 doi "https://doi.org/10.1007/978-0-387-69219-7_4" @default.
- W2265744462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17953407" @default.
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