FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2265965276> ?p ?o ?g. }

• W2265965276 endingPage "674" @default.
• W2265965276 startingPage "661" @default.
• W2265965276 abstract "β-defensins are important components of the vertebrate innate immune system responsible for encoding a variety of anti-microbial peptides. Pathogen-mediated selection is thought to act on immune genes and potentially maintain allelic variation in the face of genetic drift. The Seychelles warbler, Acrocephalus sechellensis, is an endemic passerine that underwent a recent bottleneck in its last remaining population, resulting in a considerable reduction in genome-wide variation. We genotyped avian β-defensin (AvBD) genes in contemporary (2000–2008) and museum samples (1876–1940) of the Seychelles warbler to investigate whether immunogenetic variation was lost through this bottleneck, and examined AvBD variation across four other Acrocephalus species with varying demographic histories. No variation was detected at four of the six AvBD loci screened in the post-bottleneck population of Seychelles warbler, but two silent nucleotide polymorphisms were identified at AvBD8 and one potentially functional amino-acid variation was observed at AvBD11. Variation in the Seychelles warbler was significantly lower than in the mainland migratory congeneric species investigated, but it similar to that found in other bottlenecked species. In addition, screening AvBD7 in 15 museum specimens of Seychelles warblers sampled prior to the bottleneck (1877–1905) revealed that this locus possessed two alleles previously, compared to the single allele in the contemporary population. Overall, the results show that little AvBD variation remains in the Seychelles warbler, probably as a result of having low AvBD diversity historically rather than the loss of variation due to drift associated with past demographic history. Given the limited pathogen fauna, this lack of variation at the AvBD loci may currently not pose a problem for this isolate population of Seychelles warblers, but it may be detrimental to the species’ long-term survival if new pathogens reach the population in the future." @default.
• W2265965276 created "2016-06-24" @default.
• W2265965276 creator A5004503089 @default.
• W2265965276 creator A5027860164 @default.
• W2265965276 creator A5072018988 @default.
• W2265965276 creator A5088941094 @default.
• W2265965276 date "2016-02-01" @default.
• W2265965276 modified "2023-10-03" @default.
• W2265965276 title "Avian β-defensin variation in bottlenecked populations: the Seychelles warbler and other congeners" @default.
• W2265965276 cites W1482929144 @default.
• W2265965276 cites W1533770420 @default.
• W2265965276 cites W1550819366 @default.
• W2265965276 cites W1572265772 @default.
• W2265965276 cites W1580159074 @default.
• W2265965276 cites W1584565635 @default.
• W2265965276 cites W1606183305 @default.
• W2265965276 cites W1650272193 @default.
• W2265965276 cites W1773403432 @default.
• W2265965276 cites W1782888217 @default.
• W2265965276 cites W1822956445 @default.
• W2265965276 cites W1838369584 @default.
• W2265965276 cites W1904783420 @default.
• W2265965276 cites W1905865861 @default.
• W2265965276 cites W1930545807 @default.
• W2265965276 cites W1971855129 @default.
• W2265965276 cites W1975101865 @default.
• W2265965276 cites W1977160855 @default.
• W2265965276 cites W1980680824 @default.
• W2265965276 cites W1982220354 @default.
• W2265965276 cites W1987502353 @default.
• W2265965276 cites W1994009424 @default.
• W2265965276 cites W1997152791 @default.
• W2265965276 cites W2005539754 @default.
• W2265965276 cites W2021773250 @default.
• W2265965276 cites W2027728997 @default.
• W2265965276 cites W2029977502 @default.
• W2265965276 cites W2030430005 @default.
• W2265965276 cites W2030532465 @default.
• W2265965276 cites W2033784078 @default.
• W2265965276 cites W2035845379 @default.
• W2265965276 cites W2037481858 @default.
• W2265965276 cites W2042309256 @default.
• W2265965276 cites W2065461553 @default.
• W2265965276 cites W2068020601 @default.
• W2265965276 cites W2077666076 @default.
• W2265965276 cites W2082361552 @default.
• W2265965276 cites W2083878136 @default.
• W2265965276 cites W2086564404 @default.
• W2265965276 cites W2089171422 @default.
• W2265965276 cites W2090810258 @default.
• W2265965276 cites W2098073190 @default.
• W2265965276 cites W2098822676 @default.
• W2265965276 cites W2098908016 @default.
• W2265965276 cites W2107130747 @default.
• W2265965276 cites W2108512869 @default.
• W2265965276 cites W2110270701 @default.
• W2265965276 cites W2110755408 @default.
• W2265965276 cites W2111593745 @default.
• W2265965276 cites W2111674457 @default.
• W2265965276 cites W2112559088 @default.
• W2265965276 cites W2113019085 @default.
• W2265965276 cites W2113795788 @default.
• W2265965276 cites W2113937703 @default.
• W2265965276 cites W2118422005 @default.
• W2265965276 cites W2118982822 @default.
• W2265965276 cites W2119718896 @default.
• W2265965276 cites W2120443264 @default.
• W2265965276 cites W2124462847 @default.
• W2265965276 cites W2125121305 @default.
• W2265965276 cites W2129228931 @default.
• W2265965276 cites W2130212292 @default.
• W2265965276 cites W2130783116 @default.
• W2265965276 cites W2132393729 @default.
• W2265965276 cites W2132604111 @default.
• W2265965276 cites W2133079802 @default.
• W2265965276 cites W2134984409 @default.
• W2265965276 cites W2135713132 @default.
• W2265965276 cites W2137887917 @default.
• W2265965276 cites W2138207315 @default.
• W2265965276 cites W2140028978 @default.
• W2265965276 cites W2140468698 @default.
• W2265965276 cites W2140784970 @default.
• W2265965276 cites W2144174231 @default.
• W2265965276 cites W2150501605 @default.
• W2265965276 cites W2150914878 @default.
• W2265965276 cites W2151541423 @default.
• W2265965276 cites W2152076818 @default.
• W2265965276 cites W2154158387 @default.
• W2265965276 cites W2154845780 @default.
• W2265965276 cites W2155408399 @default.
• W2265965276 cites W2160297684 @default.
• W2265965276 cites W2160695130 @default.
• W2265965276 cites W2161490972 @default.
• W2265965276 cites W2162895135 @default.
• W2265965276 cites W2164890209 @default.
• W2265965276 cites W2165767452 @default.
• W2265965276 cites W2165892911 @default.
• W2265965276 cites W2166025596 @default.

• next