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- W2267013139 abstract "Summary Expressed polymorphisms in the genes encoding components of the fibrinolytic cascade could have implications for the predisposition to thrombolytic disorders and/or for tumor metastasis. The occurrence of published two amino acid sequences at position 194 of the human urokinase-type plasminogen activator prompted us to search by SSCP for frequent polymorphisms in several exons of the gene. Surprisingly, only one sequence was detected in codon 194 (>200 alleles). Two polymorphisms were observed in this study: the most frequent one, a C to T change near the beginning of exon 8, is probably silent; a less frequent polymorphism results in the replacement of a Leu residue by a Pro, in the kringle domain." @default.
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- W2267013139 date "1997-01-01" @default.
- W2267013139 modified "2023-09-25" @default.
- W2267013139 title "Detection of Polymorphisms in the Human Urokinase-type Plasminogen Activator Gene" @default.
- W2267013139 doi "https://doi.org/10.1055/s-0038-1655983" @default.
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