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- W2267318290 abstract "A few years ago it seemed highly unlikely that homotransplantation of tissues and organs was so soon to play a significant role in the medical armamentarium, despite an enormous quantity of research dating back more than a half century. The view persisted that the severity and perseverance of homograft rejection constituted an insurmountable barrier to the successful use of alien tissue.Since 1962, these attitudes have undergone a remarkable change. More than a hundred patients throughout the world have had significant prolongation of life through functioning renal homografts. Long-term survival has been obtained in laboratory animals after homotransplantation of other organs including the liver, lung, heart, and spleen. Earlier unwarranted pessimism concerning the fate of homografts has been replaced by what, in some circles, may be viewed as overoptimism since the life expectancy of patients or animals with transplants tolerated over a long period of time is not yet known.In this communication, a brief account will be given of the results of clinical renal homotransplantation at the University of Colorado Medical Center, focusing attention only upon those patients treated from 20 to 36 months ago. A brief description of the encouraging results after experimental liver transplantation will also be included." @default.
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- W2267318290 date "1966-03-01" @default.
- W2267318290 modified "2023-09-24" @default.
- W2267318290 title "The Therapeutic Potential of Whole Organ Transplantation." @default.
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