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• W2267600681 abstract "Background: Zanthoxylum bungeanum-cake-separated moxibustion (ZBCS-moxi), a kind of traditional therapy of moxibustion, has been used&#x0D; in China since 340 B.C. However, its mechanism remains unclear. So, this study was attempted to reveal the anti-inflammatory effect of&#x0D; ZBCS-moxi on rheumatoid arthritis (RA) rats.&#x0D; Methods and Materials: Forty health SD female rats were randomly divided into 4 groups (n=10/group): control group, model group,&#x0D; Zanthoxylum bungeanum-cake-separated moxibustion group (ZBCS-moxi group) and Aconitum carmichaeli-cake-separated moxibustion group&#x0D; (ACCS-moxi group). RA model was induced by injecting 0.1 ml Freund’s complete adjuvant (FCA) into the right hind paw of rats. Eleven days&#x0D; after CFA injection, the rats in ZBCS-moxi group received Zanthoxylum bungeanum- cake-separated moxibustion on Shenshu (BL23), Zusanli&#x0D; (ST36) acupoints and the dorsum right hind paw respectively for 3 weeks. The ACCS-moxi group was used as a positive control, while the rats&#x0D; were treated with Aconitum carmichaeli-cake-separated moxibustion on the same acupoints and courses. After a 3-week treatment, we&#x0D; investigated anti-inflammatory effect by measuring the paw volume, observing the pathologic morphology of synovial membranes and detecting&#x0D; the concentration of IL-1β and TNF-α in serum.&#x0D; Results: Compared to model group, the swollen paw volumes, the synovial hyperplasia and pannus formation of synovial membranes and the&#x0D; concentration of IL-1β and TNF-α in serum decreased obviously (P" @default.
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• W2267600681 date "2015-12-03" @default.
• W2267600681 modified "2023-10-05" @default.
• W2267600681 title "ANTI-INFLAMMATORY EFFECT OF ZANTHOXYLUM BUNGEANUM-CAKE-SEPARATED MOXIBUSTION ON RHEUMATOID ARTHRITIS RATS" @default.
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• W2267600681 doi "https://doi.org/10.21010/ajtcam.v13i1.7" @default.
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