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• W2267668114 endingPage "1222" @default.
• W2267668114 startingPage "1215" @default.
• W2267668114 abstract "In this contribution we put forward a novel hypothesis concerning the aetiology of Type 2 (non-insulin dependent) diabetes mellitus. The concept underlying our hypothesis is that poor foetal and early post-natal nutrition imposes mechanisms of nutritional thrift upon the growing individual. We propose that one of the major long-term consequences of inadequate early nutrition is impaired development of the endocrine pancreas and a greatly increased susceptibility to the development of Type 2 diabetes. In the first section we outline our research which has led to this hypothesis. We will then review the relevant literature. Finally we show that the hypothesis suggests a reinterpretation of some findings and an explanation of others which are at present not easy to understand." @default.
• W2267668114 created "2016-06-24" @default.
• W2267668114 creator A5040499635 @default.
• W2267668114 creator A5079225641 @default.
• W2267668114 date "2013-10-01" @default.
• W2267668114 modified "2023-10-17" @default.
• W2267668114 title "Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis" @default.
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• W2267668114 doi "https://doi.org/10.1093/ije/dyt133" @default.
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• W2267668114 hasPublicationYear "2013" @default.
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