Matches in SemOpenAlex for { <https://semopenalex.org/work/W2267681935> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2267681935 endingPage "33" @default.
- W2267681935 startingPage "226" @default.
- W2267681935 abstract "Regio- and stereoselectivity of cytochrome P-450-mediated propranolol metabolism (4-, 5- and 7-hydroxylations and N-desisopropylation) was studied using 15 purified cytochrome P-450 species. With each purified cytochrome P-450 species, the regioselectivity was distinct and different between the two optical isomers used as substrates. The stereoselectivity was different depending on the position of propranolol to be metabolized. The regio- and stereoselectivity was altered when substrate concentration was altered, suggesting that the kinetics of the reactions are different depending on the positions of propranolol to be metabolized. Furthermore, the selectivity and its manner of alterations with substrate concentrations were different among all cytochrome P-450 species used. Propranolol, with its multiple metabolic pathways and optical isomers, is an extremely interesting substrate for characterization of cytochrome P-450 species." @default.
- W2267681935 created "2016-06-24" @default.
- W2267681935 creator A5007118600 @default.
- W2267681935 creator A5008892241 @default.
- W2267681935 creator A5013796275 @default.
- W2267681935 creator A5018898700 @default.
- W2267681935 creator A5035063726 @default.
- W2267681935 creator A5036137017 @default.
- W2267681935 creator A5045181951 @default.
- W2267681935 creator A5045285261 @default.
- W2267681935 creator A5045724582 @default.
- W2267681935 creator A5062063904 @default.
- W2267681935 date "1993-01-01" @default.
- W2267681935 modified "2023-09-23" @default.
- W2267681935 title "Regio- and stereoselective propranolol metabolism by 15 forms of purified cytochromes P-450 from rat liver." @default.
- W2267681935 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8423527" @default.
- W2267681935 hasPublicationYear "1993" @default.
- W2267681935 type Work @default.
- W2267681935 sameAs 2267681935 @default.
- W2267681935 citedByCount "8" @default.
- W2267681935 crossrefType "journal-article" @default.
- W2267681935 hasAuthorship W2267681935A5007118600 @default.
- W2267681935 hasAuthorship W2267681935A5008892241 @default.
- W2267681935 hasAuthorship W2267681935A5013796275 @default.
- W2267681935 hasAuthorship W2267681935A5018898700 @default.
- W2267681935 hasAuthorship W2267681935A5035063726 @default.
- W2267681935 hasAuthorship W2267681935A5036137017 @default.
- W2267681935 hasAuthorship W2267681935A5045181951 @default.
- W2267681935 hasAuthorship W2267681935A5045285261 @default.
- W2267681935 hasAuthorship W2267681935A5045724582 @default.
- W2267681935 hasAuthorship W2267681935A5062063904 @default.
- W2267681935 hasConcept C134018914 @default.
- W2267681935 hasConcept C161790260 @default.
- W2267681935 hasConcept C181199279 @default.
- W2267681935 hasConcept C181647583 @default.
- W2267681935 hasConcept C185592680 @default.
- W2267681935 hasConcept C18903297 @default.
- W2267681935 hasConcept C2777289219 @default.
- W2267681935 hasConcept C2778151854 @default.
- W2267681935 hasConcept C2780768313 @default.
- W2267681935 hasConcept C526171541 @default.
- W2267681935 hasConcept C55493867 @default.
- W2267681935 hasConcept C59759590 @default.
- W2267681935 hasConcept C62231903 @default.
- W2267681935 hasConcept C71240020 @default.
- W2267681935 hasConcept C86803240 @default.
- W2267681935 hasConceptScore W2267681935C134018914 @default.
- W2267681935 hasConceptScore W2267681935C161790260 @default.
- W2267681935 hasConceptScore W2267681935C181199279 @default.
- W2267681935 hasConceptScore W2267681935C181647583 @default.
- W2267681935 hasConceptScore W2267681935C185592680 @default.
- W2267681935 hasConceptScore W2267681935C18903297 @default.
- W2267681935 hasConceptScore W2267681935C2777289219 @default.
- W2267681935 hasConceptScore W2267681935C2778151854 @default.
- W2267681935 hasConceptScore W2267681935C2780768313 @default.
- W2267681935 hasConceptScore W2267681935C526171541 @default.
- W2267681935 hasConceptScore W2267681935C55493867 @default.
- W2267681935 hasConceptScore W2267681935C59759590 @default.
- W2267681935 hasConceptScore W2267681935C62231903 @default.
- W2267681935 hasConceptScore W2267681935C71240020 @default.
- W2267681935 hasConceptScore W2267681935C86803240 @default.
- W2267681935 hasIssue "1" @default.
- W2267681935 hasLocation W22676819351 @default.
- W2267681935 hasOpenAccess W2267681935 @default.
- W2267681935 hasPrimaryLocation W22676819351 @default.
- W2267681935 hasRelatedWork W114348397 @default.
- W2267681935 hasRelatedWork W1799500008 @default.
- W2267681935 hasRelatedWork W2015853466 @default.
- W2267681935 hasRelatedWork W20207240 @default.
- W2267681935 hasRelatedWork W2055277487 @default.
- W2267681935 hasRelatedWork W2108324061 @default.
- W2267681935 hasRelatedWork W2267681935 @default.
- W2267681935 hasRelatedWork W2363512936 @default.
- W2267681935 hasRelatedWork W2408203271 @default.
- W2267681935 hasRelatedWork W2419414102 @default.
- W2267681935 hasVolume "264" @default.
- W2267681935 isParatext "false" @default.
- W2267681935 isRetracted "false" @default.
- W2267681935 magId "2267681935" @default.
- W2267681935 workType "article" @default.