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- W2267765634 abstract "Objective: To exploret The clinical values of Combined Detection of homocystine, folate and Anti-cardiolipin antibodies for the prognostication of cerebral infarction. Methods: The serum levels of ACA ,Hcy and folate in 66 cases of cerebral infarction and 30 healthy people as controls were measured by ELISA and chemilum inescence immunoassay (CLIA). Results: The serum Hcy levels in patients of cerebral infarction were [(22.68±12.70)μmol/L]compared with sig nificantly higher than those in healthy controls [(13.38±2.61)μmol/L], between has significantly difference(p0.01);whereas the folate levels[(3.87±2.02)pg/ml]were significantly lower between has markable difference (p0.05)than those in healthy controls. The positive rate of Anti-cardiolipin antibodies (ACA)and hyper-homocy steinemia(Hhcy)in cerebral infarction patient swere 68.18% in cere-bral infarction patients were 53.03% there was significant difference compared with the healthy controls(16.67%)(p0.01). The sensitivity for each single of Hcy, ACA and FA in the diagnosis of cerebral infarction was 87.50% , 90.00% and 96.3% respectively, specificity was 44.60% , 54.40% and 37.09% respectively. The combined detection of Hcy, ACA and FA were superior to individual testing. Conclu sions: The high serum level of homocysteine and ACA positive is an independent risk factor for cerebral infarction. The Hhcy and Anti-cardiolipin antibodies(ACA)seem to behave as risk factors for cerebral infarction patients which may contribute to the process of patients with cerebral infarction. The combined use of Hcy, ACA and FA can help prognostication of cerebral infarction and the combined use of Hcy and ACA is the best, which have high clinical values. It is could make for prognostication of cerebral infarction." @default.
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- W2267765634 date "2010-01-01" @default.
- W2267765634 modified "2023-09-26" @default.
- W2267765634 title "Clinical values of combined detection of homocystine, folate & anti-cardiolipin antibodies in prediction of cerebral infarction" @default.
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