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- W2267993438 abstract "The objective of this work was to design mucoadhesive oral controlled release drug delivery system for ketoprofen to target the small intestine. Mucoadhesive microbeads containing Ketoprofen were prepared by ionic gelation method using sodium alginate, pectin, and xanthan gum as polymers. The prepared beads were coated with 1% chitosan solution and dried. The dried beads were filled into hard gelatin capsules and coated by a enteric polymer. All microbeads were nearly spherical in shape with rough surface with the mean particle size of 1.6 mm – 1.8 mm. Of the six formulations prepared and evaluated formulas A6 were found satisfactory results. The release followed zero order release with non-Fickian diffusion." @default.
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- W2267993438 date "2011-03-28" @default.
- W2267993438 modified "2023-09-23" @default.
- W2267993438 title "Bioadhesive Micro Beads of Ketoprofen for Controlled and Site Specific Delivery" @default.
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