Matches in SemOpenAlex for { <https://semopenalex.org/work/W2268687656> ?p ?o ?g. }
- W2268687656 abstract "The large majority of three-dimensional structures of biological macromolecules have been determined by X-ray diffraction of crystalline samples. High-resolution structure determination crucially depends on the homogeneity of the protein crystal. Overall 'rocking' motion of molecules in the crystal is expected to influence diffraction quality, and such motion may therefore affect the process of solving crystal structures. Yet, so far overall molecular motion has not directly been observed in protein crystals, and the timescale of such dynamics remains unclear. Here we use solid-state NMR, X-ray diffraction methods and μs-long molecular dynamics simulations to directly characterize the rigid-body motion of a protein in different crystal forms. For ubiquitin crystals investigated in this study we determine the range of possible correlation times of rocking motion, 0.1-100 μs. The amplitude of rocking varies from one crystal form to another and is correlated with the resolution obtainable in X-ray diffraction experiments." @default.
- W2268687656 created "2016-06-24" @default.
- W2268687656 creator A5010808086 @default.
- W2268687656 creator A5036355590 @default.
- W2268687656 creator A5049426329 @default.
- W2268687656 creator A5056849632 @default.
- W2268687656 creator A5056894395 @default.
- W2268687656 creator A5065077055 @default.
- W2268687656 creator A5069093700 @default.
- W2268687656 creator A5073138453 @default.
- W2268687656 creator A5076875040 @default.
- W2268687656 creator A5082883875 @default.
- W2268687656 creator A5091520561 @default.
- W2268687656 date "2015-10-05" @default.
- W2268687656 modified "2023-09-25" @default.
- W2268687656 title "Observing the overall rocking motion of a protein in a crystal" @default.
- W2268687656 cites W16012754 @default.
- W2268687656 cites W1915095762 @default.
- W2268687656 cites W1967007695 @default.
- W2268687656 cites W1968551119 @default.
- W2268687656 cites W1972361033 @default.
- W2268687656 cites W1975836332 @default.
- W2268687656 cites W1977013057 @default.
- W2268687656 cites W1979401635 @default.
- W2268687656 cites W1981150679 @default.
- W2268687656 cites W1984552405 @default.
- W2268687656 cites W1985613000 @default.
- W2268687656 cites W1986745504 @default.
- W2268687656 cites W1986935825 @default.
- W2268687656 cites W1987101106 @default.
- W2268687656 cites W1987429245 @default.
- W2268687656 cites W1994862123 @default.
- W2268687656 cites W1997972388 @default.
- W2268687656 cites W2010076108 @default.
- W2268687656 cites W2016370660 @default.
- W2268687656 cites W2017818056 @default.
- W2268687656 cites W2019160077 @default.
- W2268687656 cites W2019738127 @default.
- W2268687656 cites W2023921624 @default.
- W2268687656 cites W2026241642 @default.
- W2268687656 cites W2028803516 @default.
- W2268687656 cites W2029761293 @default.
- W2268687656 cites W2032907555 @default.
- W2268687656 cites W2034824964 @default.
- W2268687656 cites W2036614338 @default.
- W2268687656 cites W2041263432 @default.
- W2268687656 cites W2041432176 @default.
- W2268687656 cites W2044564338 @default.
- W2268687656 cites W2047220879 @default.
- W2268687656 cites W2050187607 @default.
- W2268687656 cites W2061612744 @default.
- W2268687656 cites W2062291001 @default.
- W2268687656 cites W2067337097 @default.
- W2268687656 cites W2067411090 @default.
- W2268687656 cites W2068498395 @default.
- W2268687656 cites W2076790509 @default.
- W2268687656 cites W2086613066 @default.
- W2268687656 cites W2087432921 @default.
- W2268687656 cites W2100251789 @default.
- W2268687656 cites W2101392123 @default.
- W2268687656 cites W2110047784 @default.
- W2268687656 cites W2115421056 @default.
- W2268687656 cites W2118807435 @default.
- W2268687656 cites W2124026197 @default.
- W2268687656 cites W2125237621 @default.
- W2268687656 cites W2127295527 @default.
- W2268687656 cites W2141378819 @default.
- W2268687656 cites W2144288821 @default.
- W2268687656 cites W2152190060 @default.
- W2268687656 cites W2152811683 @default.
- W2268687656 cites W2153250947 @default.
- W2268687656 cites W2153685013 @default.
- W2268687656 cites W2156012420 @default.
- W2268687656 cites W2157954610 @default.
- W2268687656 cites W2161605421 @default.
- W2268687656 cites W2163341755 @default.
- W2268687656 cites W2164437046 @default.
- W2268687656 cites W2171190723 @default.
- W2268687656 cites W2180229411 @default.
- W2268687656 cites W2208194134 @default.
- W2268687656 cites W2325390004 @default.
- W2268687656 cites W2621120495 @default.
- W2268687656 cites W4248872320 @default.
- W2268687656 doi "https://doi.org/10.1038/ncomms9361" @default.
- W2268687656 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4600728" @default.
- W2268687656 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26436197" @default.
- W2268687656 hasPublicationYear "2015" @default.
- W2268687656 type Work @default.
- W2268687656 sameAs 2268687656 @default.
- W2268687656 citedByCount "69" @default.
- W2268687656 countsByYear W22686876562015 @default.
- W2268687656 countsByYear W22686876562016 @default.
- W2268687656 countsByYear W22686876562017 @default.
- W2268687656 countsByYear W22686876562018 @default.
- W2268687656 countsByYear W22686876562019 @default.
- W2268687656 countsByYear W22686876562020 @default.
- W2268687656 countsByYear W22686876562021 @default.
- W2268687656 countsByYear W22686876562022 @default.
- W2268687656 countsByYear W22686876562023 @default.
- W2268687656 crossrefType "journal-article" @default.