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- W2268751260 abstract "The experiment was conducted to study the effects of dietary crude protein levels on growth performance and immune function in growing(weanling to 3 months old) laboratory rabbits.Sixty weanling(40-day-old) laboratory rabbits with an average initial body weight of(950±90) g were randomly divided into 5 groups(with 12 replicates each and 1 rabbit in each replicate) and fed the diets with crude protein levels at 12%(group Ⅰ),14%(group Ⅱ),16%(group Ⅲ),18%(group Ⅳ) and 20%(group Ⅴ),respectively.Five diets had similar content of digestible energy(10.0 MJ/kg) and crude fibre(12%).The feeding trial lasted for 42 days,and the growth performance was measured during feeding trial and the blood indices and immunological parameters were determined when the trial was finished.The results showed as follows: the relationship between average dairy gain(y) and crude protein levels(x) may be expressed as y=-0.233x2+7.637x-40.335(r=0.79,P0.01),from which the optimal average diary gain could be estimated to be at 16.4% crude protein level.The serum IGF-Ⅰ concentration in groups Ⅲ and Ⅳ was higher than that in groupⅠ(P0.05).The natural killer(NK) cell activity,spleen index and thymus index in group Ⅴ were the highest,and the above 3 indices(NK cell activity,spleen and thymus indices) in group Ⅴ were significantly higher than those in groups Ⅰ,Ⅰ and Ⅱ(P0.05),correspondingly.The stimulation index(SI) by lipopolysaccharide(LPS) in group Ⅴ was higher than that in group Ⅰ(P0.05),and the SI by concanavalin A(ConA) in group Ⅲ was higher than that in groups Ⅰ and Ⅱ(P0.05 or P0.01).Dietary crude protein levels had no significant influence on the content of immune globulin,but the concentration of IL-1β in group Ⅳ was significantly higher than that in group Ⅰ(P0.05).The activity of superoxide dismutase(SOD) and concentration of nitric oxide(NO) in groups Ⅲ and Ⅳ were significantly higher than those in group Ⅰ(P0.05 or P0.01).However,the change of maleic dialdehyde(MDA) concentration was contrary to that of SOD activity.The results indicated that 16.4% of dietary crude protein level was optimal to maintain the highest growth performance of growing laboratory rabbit,and slightly higher protein level was required to satisfy the need of immune response." @default.
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- W2268751260 date "2010-01-01" @default.
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- W2268751260 title "Effects of Dietary Crude Protein Levels on Growth Performance and Immune Function in Growing Laboratory Rabbits" @default.
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