Matches in SemOpenAlex for { <https://semopenalex.org/work/W2269295364> ?p ?o ?g. }
- W2269295364 endingPage "1120" @default.
- W2269295364 startingPage "1113" @default.
- W2269295364 abstract "The critical step in meiosis is to attach homologous chromosomes to the opposite poles. In mouse oocytes, stable microtubule end-on attachments to kinetochores are not established until hours after spindle assembly, and phosphorylation of kinetochore proteins by Aurora B/C is responsible for the delay. Here we demonstrated that microtubule ends are actively prevented from stable attachment to kinetochores until well after spindle formation in Drosophila melanogaster oocytes. We identified the microtubule catastrophe-promoting complex Sentin-EB1 as a major factor responsible for this delay. Without this activity, microtubule ends precociously form robust attachments to kinetochores in oocytes, leading to a high proportion of homologous kinetochores stably attached to the same pole. Therefore, regulation of microtubule ends provides an alternative novel mechanism to delay stable kinetochore–microtubule attachment in oocytes." @default.
- W2269295364 created "2016-06-24" @default.
- W2269295364 creator A5005718181 @default.
- W2269295364 creator A5018475349 @default.
- W2269295364 creator A5025518989 @default.
- W2269295364 creator A5043365967 @default.
- W2269295364 creator A5066080604 @default.
- W2269295364 creator A5071606159 @default.
- W2269295364 creator A5077352796 @default.
- W2269295364 creator A5086190348 @default.
- W2269295364 creator A5091017596 @default.
- W2269295364 date "2015-12-14" @default.
- W2269295364 modified "2023-09-27" @default.
- W2269295364 title "The microtubule catastrophe promoter Sentin delays stable kinetochore–microtubule attachment in oocytes" @default.
- W2269295364 cites W1501691198 @default.
- W2269295364 cites W1842102211 @default.
- W2269295364 cites W1860083681 @default.
- W2269295364 cites W1967307354 @default.
- W2269295364 cites W1981339480 @default.
- W2269295364 cites W1989307968 @default.
- W2269295364 cites W1993016853 @default.
- W2269295364 cites W2005383283 @default.
- W2269295364 cites W2022239608 @default.
- W2269295364 cites W2033797646 @default.
- W2269295364 cites W2040867342 @default.
- W2269295364 cites W2095732835 @default.
- W2269295364 cites W2097739838 @default.
- W2269295364 cites W2102831884 @default.
- W2269295364 cites W2117058735 @default.
- W2269295364 cites W2120954179 @default.
- W2269295364 cites W2124670713 @default.
- W2269295364 cites W2126460280 @default.
- W2269295364 cites W2131040585 @default.
- W2269295364 cites W2132330478 @default.
- W2269295364 cites W2133920117 @default.
- W2269295364 cites W2164835946 @default.
- W2269295364 cites W2402793346 @default.
- W2269295364 cites W4229736484 @default.
- W2269295364 doi "https://doi.org/10.1083/jcb.201507006" @default.
- W2269295364 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4687879" @default.
- W2269295364 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26668329" @default.
- W2269295364 hasPublicationYear "2015" @default.
- W2269295364 type Work @default.
- W2269295364 sameAs 2269295364 @default.
- W2269295364 citedByCount "24" @default.
- W2269295364 countsByYear W22692953642016 @default.
- W2269295364 countsByYear W22692953642017 @default.
- W2269295364 countsByYear W22692953642018 @default.
- W2269295364 countsByYear W22692953642019 @default.
- W2269295364 countsByYear W22692953642020 @default.
- W2269295364 countsByYear W22692953642021 @default.
- W2269295364 countsByYear W22692953642023 @default.
- W2269295364 crossrefType "journal-article" @default.
- W2269295364 hasAuthorship W2269295364A5005718181 @default.
- W2269295364 hasAuthorship W2269295364A5018475349 @default.
- W2269295364 hasAuthorship W2269295364A5025518989 @default.
- W2269295364 hasAuthorship W2269295364A5043365967 @default.
- W2269295364 hasAuthorship W2269295364A5066080604 @default.
- W2269295364 hasAuthorship W2269295364A5071606159 @default.
- W2269295364 hasAuthorship W2269295364A5077352796 @default.
- W2269295364 hasAuthorship W2269295364A5086190348 @default.
- W2269295364 hasAuthorship W2269295364A5091017596 @default.
- W2269295364 hasBestOaLocation W22692953641 @default.
- W2269295364 hasConcept C104317684 @default.
- W2269295364 hasConcept C148196450 @default.
- W2269295364 hasConcept C1491633281 @default.
- W2269295364 hasConcept C192838845 @default.
- W2269295364 hasConcept C20418707 @default.
- W2269295364 hasConcept C2778354886 @default.
- W2269295364 hasConcept C30481170 @default.
- W2269295364 hasConcept C47432576 @default.
- W2269295364 hasConcept C54355233 @default.
- W2269295364 hasConcept C85813293 @default.
- W2269295364 hasConcept C86803240 @default.
- W2269295364 hasConcept C95444343 @default.
- W2269295364 hasConceptScore W2269295364C104317684 @default.
- W2269295364 hasConceptScore W2269295364C148196450 @default.
- W2269295364 hasConceptScore W2269295364C1491633281 @default.
- W2269295364 hasConceptScore W2269295364C192838845 @default.
- W2269295364 hasConceptScore W2269295364C20418707 @default.
- W2269295364 hasConceptScore W2269295364C2778354886 @default.
- W2269295364 hasConceptScore W2269295364C30481170 @default.
- W2269295364 hasConceptScore W2269295364C47432576 @default.
- W2269295364 hasConceptScore W2269295364C54355233 @default.
- W2269295364 hasConceptScore W2269295364C85813293 @default.
- W2269295364 hasConceptScore W2269295364C86803240 @default.
- W2269295364 hasConceptScore W2269295364C95444343 @default.
- W2269295364 hasIssue "6" @default.
- W2269295364 hasLocation W22692953641 @default.
- W2269295364 hasLocation W22692953642 @default.
- W2269295364 hasLocation W22692953643 @default.
- W2269295364 hasLocation W22692953644 @default.
- W2269295364 hasLocation W22692953645 @default.
- W2269295364 hasOpenAccess W2269295364 @default.
- W2269295364 hasPrimaryLocation W22692953641 @default.
- W2269295364 hasRelatedWork W181256649 @default.
- W2269295364 hasRelatedWork W1968951235 @default.
- W2269295364 hasRelatedWork W2023695022 @default.