Matches in SemOpenAlex for { <https://semopenalex.org/work/W2269377332> ?p ?o ?g. }
- W2269377332 abstract "Abstract Radiation damage of biological samples remains a limiting factor in high resolution X-ray microscopy (XRM). Several studies have attempted to evaluate the extent and the effects of radiation damage, proposing strategies to minimise or prevent it. The present work aims to assess the impact of soft X-rays on formalin fixed cells on a systematic manner. The novelty of this approach resides on investigating the radiation damage not only with XRM, as often reported in relevant literature on the topic, but by coupling it with two additional independent non-destructive microscopy methods: Atomic Force Microscopy (AFM) and FTIR Microscopy (FTIRM). Human Embryonic Kidney 293 cells were exposed to different radiation doses at 1 keV. In order to reveal possible morphological and biochemical changes, the irradiated cells were systematically analysed with AFM and FTIRM before and after. Results reveal that while cell morphology is not substantially affected, cellular biochemical profile changes significantly and progressively when increasing dose, resulting in a severe breakdown of the covalent bonding network. This information impacts most soft XRM studies on fixed cells and adds an in-depth understanding of the radiation damage for developing better prevention strategies." @default.
- W2269377332 created "2016-06-24" @default.
- W2269377332 creator A5006861173 @default.
- W2269377332 creator A5027976959 @default.
- W2269377332 creator A5029374828 @default.
- W2269377332 creator A5040785660 @default.
- W2269377332 creator A5045025636 @default.
- W2269377332 creator A5060274157 @default.
- W2269377332 creator A5069785649 @default.
- W2269377332 creator A5079782243 @default.
- W2269377332 creator A5085355219 @default.
- W2269377332 date "2015-05-14" @default.
- W2269377332 modified "2023-09-26" @default.
- W2269377332 title "Soft X-Ray Microscopy Radiation Damage On Fixed Cells Investigated With Synchrotron Radiation FTIR Microscopy" @default.
- W2269377332 cites W1224158007 @default.
- W2269377332 cites W1514571039 @default.
- W2269377332 cites W1583765876 @default.
- W2269377332 cites W1973348496 @default.
- W2269377332 cites W1973594803 @default.
- W2269377332 cites W1976618506 @default.
- W2269377332 cites W1981530838 @default.
- W2269377332 cites W1984482196 @default.
- W2269377332 cites W1999808996 @default.
- W2269377332 cites W2000431734 @default.
- W2269377332 cites W2008630616 @default.
- W2269377332 cites W2016571604 @default.
- W2269377332 cites W2023626551 @default.
- W2269377332 cites W2028971906 @default.
- W2269377332 cites W2031158096 @default.
- W2269377332 cites W2032729977 @default.
- W2269377332 cites W2038785735 @default.
- W2269377332 cites W2040008235 @default.
- W2269377332 cites W2042190518 @default.
- W2269377332 cites W2043681221 @default.
- W2269377332 cites W2049734963 @default.
- W2269377332 cites W2051791505 @default.
- W2269377332 cites W2052108646 @default.
- W2269377332 cites W2056158724 @default.
- W2269377332 cites W2063973027 @default.
- W2269377332 cites W2083522386 @default.
- W2269377332 cites W2085401624 @default.
- W2269377332 cites W2086329466 @default.
- W2269377332 cites W2091584330 @default.
- W2269377332 cites W2092348451 @default.
- W2269377332 cites W2101608919 @default.
- W2269377332 cites W2103077046 @default.
- W2269377332 cites W2104214361 @default.
- W2269377332 cites W2109695616 @default.
- W2269377332 cites W2117069829 @default.
- W2269377332 cites W2117159654 @default.
- W2269377332 cites W2124827109 @default.
- W2269377332 cites W2129675664 @default.
- W2269377332 cites W2131452797 @default.
- W2269377332 cites W2137089455 @default.
- W2269377332 cites W2140216106 @default.
- W2269377332 cites W2145345606 @default.
- W2269377332 cites W2160564267 @default.
- W2269377332 cites W2330239275 @default.
- W2269377332 cites W2411022054 @default.
- W2269377332 cites W2479715393 @default.
- W2269377332 cites W4249815350 @default.
- W2269377332 doi "https://doi.org/10.1038/srep10250" @default.
- W2269377332 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4431353" @default.
- W2269377332 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25974639" @default.
- W2269377332 hasPublicationYear "2015" @default.
- W2269377332 type Work @default.
- W2269377332 sameAs 2269377332 @default.
- W2269377332 citedByCount "52" @default.
- W2269377332 countsByYear W22693773322016 @default.
- W2269377332 countsByYear W22693773322017 @default.
- W2269377332 countsByYear W22693773322018 @default.
- W2269377332 countsByYear W22693773322019 @default.
- W2269377332 countsByYear W22693773322020 @default.
- W2269377332 countsByYear W22693773322021 @default.
- W2269377332 countsByYear W22693773322022 @default.
- W2269377332 countsByYear W22693773322023 @default.
- W2269377332 crossrefType "journal-article" @default.
- W2269377332 hasAuthorship W2269377332A5006861173 @default.
- W2269377332 hasAuthorship W2269377332A5027976959 @default.
- W2269377332 hasAuthorship W2269377332A5029374828 @default.
- W2269377332 hasAuthorship W2269377332A5040785660 @default.
- W2269377332 hasAuthorship W2269377332A5045025636 @default.
- W2269377332 hasAuthorship W2269377332A5060274157 @default.
- W2269377332 hasAuthorship W2269377332A5069785649 @default.
- W2269377332 hasAuthorship W2269377332A5079782243 @default.
- W2269377332 hasAuthorship W2269377332A5085355219 @default.
- W2269377332 hasBestOaLocation W22693773321 @default.
- W2269377332 hasConcept C111337013 @default.
- W2269377332 hasConcept C120665830 @default.
- W2269377332 hasConcept C121332964 @default.
- W2269377332 hasConcept C12554922 @default.
- W2269377332 hasConcept C147080431 @default.
- W2269377332 hasConcept C153385146 @default.
- W2269377332 hasConcept C153428861 @default.
- W2269377332 hasConcept C16332341 @default.
- W2269377332 hasConcept C185544564 @default.
- W2269377332 hasConcept C192562407 @default.
- W2269377332 hasConcept C2779328170 @default.
- W2269377332 hasConcept C86803240 @default.
- W2269377332 hasConceptScore W2269377332C111337013 @default.