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- W2270293993 abstract "A chromosome pulverization phenomenon was induced in Chinese hamster cells by infecting cultures with Sendai virus. Striking cellular responses to virus, in terms of chromosome pulverization and syncytium formation, were observed as early as 30 minutes after treatment of the cells with virus. It is suggested that syncytial formation is a prerequisite for the induction of chromosome pulverization. After an initial response, the cells appeared to lose promptly the high susceptibility to pulverization-inducing factors. The latter were proved to be present constantly in the culture medium during the culture period. The syncytium formation depended on virus dosage, but the pulverization phenomenon occurred at a constant ratio and pattern, regardless of the dosage of virus. It is likely that only a definite proportion of cells in the culture may be able to participate in the induction of the pulverization phenomenon." @default.
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- W2270293993 date "1968-11-01" @default.
- W2270293993 modified "2023-09-27" @default.
- W2270293993 title "Chromosome Pulverization in Chinese Hamster Cells Induced by Sendai Virus<xref ref-type=fn rid=FN2>2</xref>" @default.
- W2270293993 doi "https://doi.org/10.1093/jnci/41.5.1117" @default.
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