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• W2270597898 abstract "The bicuspid aortic valve (BAV) affects 1–2% of the population and may be associated with important valvular disease and an increased risk of aortic root and/or ascending aortic aneurysm and dissection. BAV aortic aneurysm and dissection occur earlier in life than when these disorders are associated with a tricuspid aortic valve (TAV). Alterations in the aortic media and differences in aortic elastic properties and wall stress also accompany BAV aortopathy. With appropriate follow-up and timely surgery, population studies have documented a survival rate for patients with BAV no different from age-matched controls. Guidelines have previously recommended prophylactic aortic surgery at a smaller aortic aneurysm size for patients with BAV compared with aneurysms in patients with a TAV. Recent guidelines have presented differing indications regarding the appropriate timing of prophylactic surgery for BAV aneurysms, giving the recommendation for surgery when the aortic root and/or ascending aortic exceeds 5.5 cm (unless certain factors are present), the same size for which TAV-associated aortic aneurysm surgery is recommended. We review the pathophysiology of BAV aortopathy, the clinical history of BAV ascending aortic disease, areas of uncertainty and make a case for a patient-centered, individualised decision regarding the optimal timing of aortic aneurysm surgery in BAV disease." @default.
• W2270597898 created "2016-06-24" @default.
• W2270597898 creator A5086538877 @default.
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• W2270597898 date "2015-06-15" @default.
• W2270597898 modified "2023-09-27" @default.
• W2270597898 title "Surgical threshold for bicuspid aortic valve aneurysm: a case for individual decision-making" @default.
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• W2270597898 doi "https://doi.org/10.1136/heartjnl-2014-306601" @default.
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