Matches in SemOpenAlex for { <https://semopenalex.org/work/W2270704501> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W2270704501 abstract "It is generally agreed that systolic performance of a heart chamber is the fractional inward displacement of its wall during contraction and that this depends on preload, afterload, and characteristics of the relation between afterload and end-ejection dimensions. However, there is no consensus on the details of this statement. How can one define and identify the wall element, the displacement of which best expresses performance? What is preload? What parameters best characterize the relation between afterload and end-ejection dimensions? Dividing a thick-wall compliance equation by a thick-wall pressure equation reveals the midwall element, the normalized displacements of which depend consistently on normalized pressure changes according to wall properties regardless of wall-to-cavity ratio. This midwall element's reference dimensions best express chamber size, its reference-normalized dimensions best express wall stretch or distension, and its fractional displacements best express systolic performance. The hydraulically unloaded state is a poor reference for expressing size, normalizing dimensions, and defining chamber characteristics; it is inaccessible, immeasurable, acutely variable, and not a mechanically unloaded state. Therefore stiffness is neither a characteristic nor an expression of systolic vigor. A better reference state is the average basal end-diastolic distension to which the chamber is accustomed; it is accessible, measurable, and a state where stretches throughout the wall are near a characteristic value. End-diastolic midwall dimension relative to its average basal value is a valid expression of preload. There are two main hydrodynamic characteristics expressing systolic vigor: 1) peak isovolumic pressure at reference distension and 2) displacement from reference distension if afterload were zero. An additional characteristic is shape of the pressure-volume relation. It appears possible to account for systolic performance in terms of preload, afterload, and these hydrodynamic characteristics." @default.
- W2270704501 created "2016-06-24" @default.
- W2270704501 creator A5088108209 @default.
- W2270704501 date "1989-12-01" @default.
- W2270704501 modified "2023-09-25" @default.
- W2270704501 title "Evaluation of systolic effectiveness and its determinants: pressure/midwall-volume relations" @default.
- W2270704501 doi "https://doi.org/10.1152/ajpheart.1989.257.6.h2070" @default.
- W2270704501 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2603990" @default.
- W2270704501 hasPublicationYear "1989" @default.
- W2270704501 type Work @default.
- W2270704501 sameAs 2270704501 @default.
- W2270704501 citedByCount "7" @default.
- W2270704501 crossrefType "journal-article" @default.
- W2270704501 hasAuthorship W2270704501A5088108209 @default.
- W2270704501 hasConcept C121332964 @default.
- W2270704501 hasConcept C123576724 @default.
- W2270704501 hasConcept C126322002 @default.
- W2270704501 hasConcept C164705383 @default.
- W2270704501 hasConcept C178853913 @default.
- W2270704501 hasConcept C192562407 @default.
- W2270704501 hasConcept C2776625112 @default.
- W2270704501 hasConcept C2777953023 @default.
- W2270704501 hasConcept C33923547 @default.
- W2270704501 hasConcept C48277249 @default.
- W2270704501 hasConcept C57879066 @default.
- W2270704501 hasConcept C65882447 @default.
- W2270704501 hasConcept C71924100 @default.
- W2270704501 hasConcept C80461066 @default.
- W2270704501 hasConcept C84393581 @default.
- W2270704501 hasConceptScore W2270704501C121332964 @default.
- W2270704501 hasConceptScore W2270704501C123576724 @default.
- W2270704501 hasConceptScore W2270704501C126322002 @default.
- W2270704501 hasConceptScore W2270704501C164705383 @default.
- W2270704501 hasConceptScore W2270704501C178853913 @default.
- W2270704501 hasConceptScore W2270704501C192562407 @default.
- W2270704501 hasConceptScore W2270704501C2776625112 @default.
- W2270704501 hasConceptScore W2270704501C2777953023 @default.
- W2270704501 hasConceptScore W2270704501C33923547 @default.
- W2270704501 hasConceptScore W2270704501C48277249 @default.
- W2270704501 hasConceptScore W2270704501C57879066 @default.
- W2270704501 hasConceptScore W2270704501C65882447 @default.
- W2270704501 hasConceptScore W2270704501C71924100 @default.
- W2270704501 hasConceptScore W2270704501C80461066 @default.
- W2270704501 hasConceptScore W2270704501C84393581 @default.
- W2270704501 hasLocation W22707045011 @default.
- W2270704501 hasLocation W22707045012 @default.
- W2270704501 hasOpenAccess W2270704501 @default.
- W2270704501 hasPrimaryLocation W22707045011 @default.
- W2270704501 hasRelatedWork W1501289011 @default.
- W2270704501 hasRelatedWork W1607132732 @default.
- W2270704501 hasRelatedWork W1980192127 @default.
- W2270704501 hasRelatedWork W1981655888 @default.
- W2270704501 hasRelatedWork W2044923150 @default.
- W2270704501 hasRelatedWork W2094729989 @default.
- W2270704501 hasRelatedWork W2098647735 @default.
- W2270704501 hasRelatedWork W2270704501 @default.
- W2270704501 hasRelatedWork W2426458320 @default.
- W2270704501 hasRelatedWork W3130543250 @default.
- W2270704501 isParatext "false" @default.
- W2270704501 isRetracted "false" @default.
- W2270704501 magId "2270704501" @default.
- W2270704501 workType "article" @default.